Reaction profile

The FDA adverse-event record for red mucosae

79 FDA adverse-event reports reference red mucosae (VeDDRA 1003). See the species, breeds, and drugs most associated with it below.

79
reports citing this reaction
22.8%
death-coded share
Dog
most-affected species
Milbemycin Oxime + Spinosad
most-associated drug
Verify with FDA CVM →
79
Total Reports
18
Deaths
22.8%
Death Rate

Species Most Affected

Dog 67
Horse 6
Cat 5
Unknown 1

Breeds Most Affected

Shepherd Dog - German 6
Boxer (German Boxer) 6
Retriever - Labrador 5
Terrier - Bull - American Pit 5
Crossbred Canine/dog 4
Dachshund (unspecified) 3
Domestic Shorthair 3
Chihuahua 3
Siberian Husky 2
Terrier - Jack Russell 2

Associated Drugs

Milbemycin Oxime + Spinosad 10
Moxidectin 8
Pyrantel Pamoate;Sarolaner 6
Propofol 6
Ivermectin(1.55%)/Praziquantel(7.75%) Paste 5
Maropitant Citrate 5
Buprenorphine 5
Trazodone 5
Spinosad 4
Prednisone 4
Rabies Virus, 4
Carprofen 4
Butorphanol 4
Acepromazine 4
Cefazolin 4
Leptospira Canicola L-15 Strain C-51;Leptospira Grippotyphosa 1550 Lot 10005 Str 3
Bordetella Bronchiseptica, Strain 78-9159 3
Sarolaner 3
Phenylpropropanolamine Hcl 3
Gabapentin 3

Red mucosae Reaction Insights

79 reports name Red mucosae; 18 recorded a death outcome (22.8% of reported events, not a population-level mortality rate). VeDDRA code: 1003.

By species: Dog (67 reports), Horse (6 reports), Cat (5 reports). By breed: Shepherd Dog - German (6), Boxer (German Boxer) (6), Retriever - Labrador (5).

Most co-reported drugs: Milbemycin Oxime + Spinosad (10 reports), Moxidectin (8 reports), Pyrantel Pamoate;Sarolaner (6 reports), Propofol (6 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.