Reaction profile

The FDA adverse-event record for metabolism and nutrition disorder nos

19 FDA reports name metabolism and nutrition disorder nos, a lower-volume reaction in the CVM extract (VeDDRA 2019). Plate stamps and neighbourhood peers follow.

#2188 of 2,481
by report volume (all reactions)
19
reports citing this reaction
47.4%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Metabolism and nutrition disorder NOS has 19 reports now versus 19 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Metabolism and nutrition disorder NOS changes

FDA AER · VeDDRA plate

Code 2019 VOL-TRACE

VOL-TRACE · DEATH-HOT · LOWER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-TRACE 19 reports
  • DEATH-HOT 47.4%
  • LOWER-Q #2188/2481
  • PHOTO-FINISH Adaptor, damaged
  • SPECIES-DOG Dog · 12
  • DRUG-LEAD Milbemycin Oxime… · 3
  • DESK-WIDE 16 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Adaptor, damaged (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Lower-volume neighbourhood around Metabolism and nutrition disorder NOS

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Adaptor, damaged · near19Amaurosis (see also P… · near19Anhidrosis · near19Cholelithiasis · near19Metabolism and nutrit… · thi…19Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Metabolism and nutrition disorder NOS

Metabolism and nutrition disorder NOS: high death-coded share in the FDA AER plate

Signature read: 19 reports place Metabolism and nutrition disorder NOS in the lower third of FDA AER volume (#2188 of 2,481). Report volume is lower-third scale: 19 named reports in the openFDA extract. Death-coded share is upper-third: 9 of 19 reports (47.4% of named reports). Nearest volume peer: Adaptor, damaged (±0 reports). Lead species Dog (12). Lead co-reported drug Milbemycin Oxime + Spinosad (3).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 12
Cattle 4
Unknown 1
Turkey 1
Horse 1

Breeds Most Affected

Chihuahua 2
Cattle (other) 2
Boxer (German Boxer) 2
Sheepdog - Shetland 1
Poodle - Standard 1
Unknown 1
Schnauzer - Miniature 1
Dachshund - Miniature 1
Mixed (Cattle) 1
Brangus 1

Associated Drugs

Milbemycin Oxime + Spinosad 3
Carprofen 3
Imidacloprid + Moxidectin 1
Tulathromycin 1
Milbemycin Oxime 1
Tylosin Tartrate 1
Alprazolam 1
Spinosad 1
Trilostane 1
Sam-E 1
Pyrantel Pamoate/Praziquantel 1
Decoquinate 1
Doramectin 1
Leptospira Canicola L-15 Strain C-51;Leptospira Grippotyphosa 1550 Lot 10005 Str 1
Bovine Parainfluenza 3, Pi3 Ebk-1/Ebht-1 Strain Al-Im;Infectious Bovine Rhinotra 1
Lasalocid Sodium 1
Afoxolaner 1
Selamectin 1
Propofol 1
Isoflurane 1

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Metabolism and nutrition disorder NOS (#2188 of 2,481 by report volume); death-coded 47.4%. PlainBreed reaction plate · report volume stamp 19 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →