Reaction profile

The FDA adverse-event record for gingivitis

279 FDA adverse-event reports reference gingivitis (VeDDRA 286). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#903 of 2,481
by report volume (all reactions)
279
reports citing this reaction
9.7%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Gingivitis has 279 reports now versus 276 in that prior snapshot: 3 more (1.1%).

Report change
+3
Death-coded reports
+0
Death-coded share
−0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Gingivitis changes

FDA AER · VeDDRA plate

Code 286 VOL-LOW

VOL-LOW · DEATH-PAR · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 279 reports
  • DEATH-PAR 9.7%
  • MID-PACK #903/2481
  • PHOTO-FINISH Atopic allergy NOS (s…
  • SPECIES-DOG Dog · 173
  • DRUG-LEAD Milbemycin Oxime… · 29
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Atopic allergy NOS (see also 'Skin') (±1 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Gingivitis

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Bloated stomach · near282Atopic allergy NOS (s… · near280Gingivitis · this reaction279Bad taste · near278Rigidity of limbs · near277Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Gingivitis

What the FDA AER plate says about Gingivitis

Signature read: report volume at 279 (#903 of 2,481) is the standout scale stamp on Gingivitis. Report volume sits in the middle third of the reaction corpus. 27 of 279 reports were death-coded (9.7% of named reports, not a population mortality rate). Nearest volume peer: Atopic allergy NOS (see also 'Skin') (±1 reports). Lead species Dog (173). Lead co-reported drug Milbemycin Oxime + Spinosad (29).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Milbemycin Oxime + Spinosad appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 173
Cat 92
Horse 14

Breeds Most Affected

Domestic Shorthair 61
Crossbred Canine/dog 18
Retriever - Labrador 14
Domestic Mediumhair 9
Chihuahua 9
Maltese 8
Dachshund (unspecified) 7
Shih Tzu 7
Shepherd Dog - German 5
Siamese 5

Associated Drugs

Milbemycin Oxime + Spinosad 29
Trilostane 28
Rabies Vaccine 23
Cyclosporine 19
Maropitant Citrate 18
Milbemycin Oxime + Praziquantel 17
Gabapentin 17
Unspecified 17
Spinosad 14
Cyclosporine A 14
Bexagliflozin 13
Selamectin 12
Robenacoxib 11
Imidacloprid + Moxidectin 11
Carprofen 10
Butorphanol 10
Bordetella Vaccine 9
Nitenpyram 9
Afoxolaner 9
Oclacitinib Maleate 9

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Gingivitis, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (279 here).

Similar death-coded share

Nearest other reactions by death-coded share (9.7% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Gingivitis (#903 of 2,481 by report volume); death-coded 9.7%. PlainBreed reaction plate · report volume stamp 279 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →