Abdominal discomfort

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VeDDRA Code: 2010

777 adverse event reports referencing this reaction

777
Total Reports
116
Deaths
1490.0%
Death Rate

Species Most Affected

Dog 633
Cat 82
Horse 43
Human 10
Cattle 9

Breeds Most Affected

Retriever - Labrador 69
Domestic Shorthair 52
Crossbred Canine/dog 51
Terrier - Yorkshire 28
Chihuahua 26
Boxer (German Boxer) 25
Shih Tzu 25
Shepherd Dog - German 19
Retriever - Golden 18
Dachshund (unspecified) 18

Associated Drugs

Milbemycin Oxime + Spinosad 148
Carprofen 66
Maropitant Citrate 63
Deracoxib 38
Trilostane 35
Spinosad 35
Gabapentin 30
Meloxicam 30
Oclacitinib Maleate 30
Fluralaner Chew Tablets 30
Tramadol 29
Afoxolaner 24
Moxidectin 22
Milbemycin Oxime + Praziquantel 22
Cyclosporine A 20
Famotidine 19
Ivermectin + Pyrantel As Pamoate Salt 19
Selamectin 18
Buprenorphine 18
Grapiprant 18

Data Summary

Metric Value
Total reports referencing reaction 777
Reports with fatal outcome 116
Case-fatality rate (reported events) 1490.0%
Species observed 5
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 2010.

Abdominal discomfort Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 777 adverse event reports that reference Abdominal discomfort as a reaction term, including 116 reports with a death outcome — a 1490.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 2010, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Abdominal discomfort appears most frequently in reports for Dog (633 reports), Cat (82 reports), Horse (43 reports) — with Dog dominating at 633 entries. Within those species, the breeds most often named alongside this reaction are Retriever - Labrador (69), Domestic Shorthair (52), Crossbred Canine/dog (51). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Abdominal discomfort are Milbemycin Oxime + Spinosad (148 reports), Carprofen (66 reports), Maropitant Citrate (63 reports), Deracoxib (38 reports), with Milbemycin Oxime + Spinosad appearing alongside this reaction in 148 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial