Reaction profile

The FDA adverse-event record for right ventricular dilatation

21 FDA adverse-event reports reference right ventricular dilatation (VeDDRA 203). See the species, breeds, and drugs most associated with it below.

21
reports citing this reaction
71.4%
death-coded share
Dog
most-affected species
Milbemycin Oxime + Spinosad
most-associated drug
Verify with FDA CVM →
21
Total Reports
15
Deaths
71.4%
Death Rate

Species Most Affected

Dog 16
Cat 4
Rabbit 1

Breeds Most Affected

Siamese 3
Shepherd Dog - Belgian Malinois 2
Terrier - Bull - American Pit 1
Setter - English 1
Corgi - Welsh Cardigan 1
Retriever - Golden 1
Crossbred Canine/dog 1
Terrier - Jack Russell 1
Pointing Dog - German Short-haired 1
Retriever - Labrador 1

Associated Drugs

Milbemycin Oxime + Spinosad 4
Spinosad 3
Fluralaner Chew Tablets 3
Cefovecin Sodium 2
Maropitant Citrate 2
Bedinvetmab 2
Oclacitinib Maleate 2
Gabapentin 2
Tramadol 2
Metabolic Plus Mobility Prescription Diet 2
Keppra 2
Ivermectin + Pyrantel 1
Ivermectin 1
Methylprednisone Acetate 1
Pradofloxacin 1
Clindamycin 1
Dextrose 1
Cyproheptadine 1
Fluids 1
Trimethoprim-Sulfadiazine 1

Right ventricular dilatation Reaction Insights

21 reports name Right ventricular dilatation; 15 recorded a death outcome (71.4% of reported events, not a population-level mortality rate). VeDDRA code: 203.

By species: Dog (16 reports), Cat (4 reports), Rabbit (1 reports). By breed: Siamese (3), Shepherd Dog - Belgian Malinois (2), Terrier - Bull - American Pit (1).

Most co-reported drugs: Milbemycin Oxime + Spinosad (4 reports), Spinosad (3 reports), Fluralaner Chew Tablets (3 reports), Cefovecin Sodium (2 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.