Right ventricular dilatation

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VeDDRA Code: 203

21 adverse event reports referencing this reaction

21
Total Reports
15
Deaths
7140.0%
Death Rate

Species Most Affected

Dog 16
Cat 4
Rabbit 1

Breeds Most Affected

Siamese 3
Shepherd Dog - Belgian Malinois 2
Terrier - Bull - American Pit 1
Setter - English 1
Corgi - Welsh Cardigan 1
Retriever - Golden 1
Crossbred Canine/dog 1
Terrier - Jack Russell 1
Pointing Dog - German Short-haired 1
Retriever - Labrador 1

Associated Drugs

Milbemycin Oxime + Spinosad 4
Spinosad 3
Fluralaner Chew Tablets 3
Cefovecin Sodium 2
Maropitant Citrate 2
Bedinvetmab 2
Oclacitinib Maleate 2
Gabapentin 2
Tramadol 2
Metabolic Plus Mobility Prescription Diet 2
Keppra 2
Ivermectin + Pyrantel 1
Ivermectin 1
Methylprednisone Acetate 1
Pradofloxacin 1
Clindamycin 1
Dextrose 1
Cyproheptadine 1
Fluids 1
Trimethoprim-Sulfadiazine 1

Data Summary

Metric Value
Total reports referencing reaction 21
Reports with fatal outcome 15
Case-fatality rate (reported events) 7140.0%
Species observed 3
Breeds observed 18
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 203.

Right ventricular dilatation Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 21 adverse event reports that reference Right ventricular dilatation as a reaction term, including 15 reports with a death outcome — a 7140.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 203, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Right ventricular dilatation appears most frequently in reports for Dog (16 reports), Cat (4 reports), Rabbit (1 reports) — with Dog dominating at 16 entries. Within those species, the breeds most often named alongside this reaction are Siamese (3), Shepherd Dog - Belgian Malinois (2), Terrier - Bull - American Pit (1). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Right ventricular dilatation are Milbemycin Oxime + Spinosad (4 reports), Spinosad (3 reports), Fluralaner Chew Tablets (3 reports), Cefovecin Sodium (2 reports), with Milbemycin Oxime + Spinosad appearing alongside this reaction in 4 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial