Reaction profile

The FDA adverse-event record for paralysis

450 FDA adverse-event reports reference paralysis (VeDDRA 696). See the species, breeds, and drugs most associated with it below.

450
reports citing this reaction
46.9%
death-coded share
Dog
most-affected species
Bedinvetmab
most-associated drug
Verify with FDA CVM →
450
Total Reports
211
Deaths
46.9%
Death Rate

Species Most Affected

Dog 356
Cat 54
Cattle 17
Turkey 7
Chicken 3
Rabbit 3
Horse 3
Pig 2
Human 2
Turtle 1

Breeds Most Affected

Retriever - Labrador 41
Crossbred Canine/dog 30
Domestic Shorthair 30
Dog (unknown) 27
Chihuahua 20
Dachshund (unspecified) 14
Retriever - Golden 14
Terrier - Yorkshire 13
Shepherd Dog - German 11
Shih Tzu 11

Associated Drugs

Bedinvetmab 83
Carprofen 75
Milbemycin Oxime + Spinosad 37
Gabapentin 32
Afoxolaner 27
Moxidectin 16
Cefovecin 16
Fluralaner Chew Tablets 16
Spinosad 15
Prednisone 14
Sarolaner 14
Selamectin 13
Monensin Sodium 13
Maropitant Citrate 13
Ivermectin 11
Melarsomine Dihydrochloride 10
Tramadol 10
Pyrantel Pamoate;Sarolaner 10
Enrofloxacin 9
Grapiprant 9

Paralysis Reaction Insights

450 reports name Paralysis; 211 recorded a death outcome (46.9% of reported events, not a population-level mortality rate). VeDDRA code: 696.

By species: Dog (356 reports), Cat (54 reports), Cattle (17 reports). By breed: Retriever - Labrador (41), Crossbred Canine/dog (30), Domestic Shorthair (30).

Most co-reported drugs: Bedinvetmab (83 reports), Carprofen (75 reports), Milbemycin Oxime + Spinosad (37 reports), Gabapentin (32 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.