Reaction profile

The FDA adverse-event record for semi-conscious

40 FDA reports name semi-conscious, a lower-volume reaction in the CVM extract (VeDDRA 1738). Plate stamps and neighbourhood peers follow.

#1853 of 2,481
by report volume (all reactions)
40
reports citing this reaction
35.0%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Semi-conscious has 40 reports now versus 40 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Semi-conscious changes

FDA AER · VeDDRA plate

Code 1738 VOL-TRACE

VOL-TRACE · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-TRACE 40 reports
  • DEATH-HOT 35.0%
  • MID-PACK #1853/2481
  • PHOTO-FINISH Acute (interstitial)…
  • SPECIES-DOG Dog · 30
  • DRUG-LEAD Spinosad · 6
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Acute (interstitial) pneumonia/pleuropneumonia (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Lower-volume neighbourhood around Semi-conscious

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Acute (interstitial)… · near40Anxious state of mind · near40Direct Coombs test, p… · near40Endocrine neoplasm · near40Semi-conscious · this reacti…40Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Semi-conscious

Semi-conscious: high death-coded share in the FDA AER plate

Signature read: Semi-conscious's 35.0% death-coded share is among the highest in the openFDA reaction corpus. Report volume is lower-third scale: 40 named reports in the openFDA extract. Death-coded share is upper-third: 14 of 40 reports (35.0% of named reports). Nearest volume peer: Acute (interstitial) pneumonia/pleuropneumonia (±0 reports). Lead species Dog (30). Lead co-reported drug Spinosad (6).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 30
Cat 10

Breeds Most Affected

Domestic Shorthair 6
Terrier (unspecified) 3
Retriever - Labrador 3
Shih Tzu 2
Crossbred Canine/dog 2
Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog) 2
Domestic Mediumhair 2
Hound (unspecified) 1
Havanese 1
Cat (unknown) 1

Associated Drugs

Spinosad 6
Milbemycin Oxime + Spinosad 5
Ivermectin 3
Robenacoxib 3
Buprenorphine 3
Maropitant Citrate 2
Fluralaner Chew Tablets 2
Prednisone 2
Gabapentin 2
Fluralaner Spot-On Solution 2
Dexmedetomidine,Ketamine,Butorphanol 2
Bedinvetmab 2
Melarsomine Dihydrochloride Injection 1
Cefovecin Sodium 1
Methylprednisone Acetate 1
Chlorhexidine Shampoo 1
Deracoxib 1
Firocoxib 1
Sarolaner 1
Emodepside + Praziquantel 1

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Semi-conscious (#1853 of 2,481 by report volume); death-coded 35.0%. PlainBreed reaction plate · death-coded share stamp 35.0% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →