Immune mediated haemolytic anaemia

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VeDDRA Code: 1896

1,395 adverse event reports referencing this reaction

1,395
Total Reports
515
Deaths
3690.0%
Death Rate

Species Most Affected

Dog 1,277
Cat 114
Horse 4

Breeds Most Affected

Retriever - Labrador 106
Crossbred Canine/dog 104
Shih Tzu 71
Domestic Shorthair 60
Dog (unknown) 54
Chihuahua 53
Dachshund (unspecified) 42
Spaniel - Cocker American 38
Shepherd Dog - German 37
Maltese 36

Associated Drugs

Moxidectin 243
Carprofen 146
Prednisone 125
Maropitant Citrate 120
Milbemycin Oxime + Spinosad 101
Bedinvetmab 98
Cefovecin 95
Afoxolaner 73
Doxycycline 66
Fluralaner Chew Tablets 65
Oclacitinib Maleate 61
Cyclosporine 55
Pyrantel Pamoate;Sarolaner 50
Spinosad 48
Gabapentin 47
Anti-Il31 Mab Mcs Lot #1283563 44
Leptospira Canicola L-15 Strain C-51;Leptospira Grippotyphosa 1550 Lot 10005 Str 44
Famotidine 41
Dexamethasone 40
Rabies Virus, Kv 39

Data Summary

Metric Value
Total reports referencing reaction 1,395
Reports with fatal outcome 515
Case-fatality rate (reported events) 3690.0%
Species observed 3
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 1896.

Immune mediated haemolytic anaemia Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 1,395 adverse event reports that reference Immune mediated haemolytic anaemia as a reaction term, including 515 reports with a death outcome — a 3690.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 1896, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Immune mediated haemolytic anaemia appears most frequently in reports for Dog (1,277 reports), Cat (114 reports), Horse (4 reports) — with Dog dominating at 1,277 entries. Within those species, the breeds most often named alongside this reaction are Retriever - Labrador (106), Crossbred Canine/dog (104), Shih Tzu (71). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Immune mediated haemolytic anaemia are Moxidectin (243 reports), Carprofen (146 reports), Prednisone (125 reports), Maropitant Citrate (120 reports), with Moxidectin appearing alongside this reaction in 243 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial