Reaction profile

The FDA adverse-event record for pharyngeal oedema

56 FDA adverse-event reports reference pharyngeal oedema (VeDDRA 1224). See the species, breeds, and drugs most associated with it below.

56
reports citing this reaction
32.1%
death-coded share
Dog
most-affected species
Cefovecin Sodium
most-associated drug
Verify with FDA CVM →
56
Total Reports
18
Deaths
32.1%
Death Rate

Species Most Affected

Dog 25
Cat 11
Horse 9
Human 9
Cattle 2

Breeds Most Affected

Unknown 9
Domestic Shorthair 4
Quarter Horse 3
Domestic (unspecified) 3
Boxer (German Boxer) 3
Spitz - German Pomeranian 3
Standardbred (unspecified) 2
Dog (unknown) 2
Bulldog 2
Terrier - West Highland White 2

Associated Drugs

Cefovecin Sodium 6
Moxidectin 4
Diphenhydramine Hcl 4
Ivermectin, Praziquantel 3
Imidacloprid + Moxidectin 3
Maropitant Citrate 3
Ceftiofur Crystalline Free Acid 3
Canine Adenovirus Type 2, Strain Manhattan, 12-13-76; Canine Distemper Virus, St 3
Dexamethasone 3
Maropitant 2
Acepromazine Maleate 2
Penicillin G Procaine 2
Selamectin 2
Pyrantel Pamoate (Pyrantel Embonate) 2
Rabies Virus, Kv 2
Ilunocitinib 2
Milbemycin Oxime, Praziquantel 2
Oclacitinib Maleate 2
Salicylic Acid, Disodium Edta,Docusate Sodium,Pcmx,L-Rhamnose,D-Galactose,D-Mannose,Fdc Blue 1 2
Canine Interleukin-31 Monoclonal Antibody 2

Pharyngeal oedema Reaction Insights

56 reports name Pharyngeal oedema; 18 recorded a death outcome (32.1% of reported events, not a population-level mortality rate). VeDDRA code: 1224.

By species: Dog (25 reports), Cat (11 reports), Horse (9 reports). By breed: Unknown (9), Domestic Shorthair (4), Quarter Horse (3).

Most co-reported drugs: Cefovecin Sodium (6 reports), Moxidectin (4 reports), Diphenhydramine Hcl (4 reports), Ivermectin, Praziquantel (3 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.