Reaction profile

The FDA adverse-event record for injection site paraesthesia

13 FDA reports name injection site paraesthesia, a lower-volume reaction in the CVM extract (VeDDRA 1548). Plate stamps and neighbourhood peers follow.

#2358 of 2,481
by report volume (all reactions)
13
reports citing this reaction
0.0%
death-coded share
Human
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Injection site paraesthesia has 13 reports now versus 13 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Injection site paraesthesia changes

FDA AER · VeDDRA plate

Code 1548 VOL-TRACE

VOL-TRACE · DEATH-RARE · BOTTOM-DECILE · PHOTO-FINISH · SPECIES-HUMAN · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-TRACE 13 reports
  • DEATH-RARE 0.0%
  • BOTTOM-DECILE #2358/2481
  • PHOTO-FINISH Abnormal digital pulse
  • SPECIES-HUMAN Human · 6
  • DRUG-LEAD Ceftiofur Crystal… · 2
  • DESK-WIDE 8 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Abnormal digital pulse (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Lower-volume neighbourhood around Injection site paraesthesia

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Abnormal digital pulse · near13Acute haemorrhagic pa… · near13Acute jaundice · near13Application site mass… · near13Injection site paraes… · thi…13Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Injection site paraesthesia

Injection site paraesthesia: low death-coded share in the FDA AER plate

Signature read: 13 reports place Injection site paraesthesia in the lower third of FDA AER volume (#2358 of 2,481). Report volume is lower-third scale: 13 named reports in the openFDA extract. Death-coded share is lower-third: 0 of 13 reports (0.0% of named reports). Nearest volume peer: Abnormal digital pulse (±0 reports). Lead species Human (6). Lead co-reported drug Ceftiofur Crystalline Free Acid (2).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Ceftiofur Crystalline Free Acid appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Human 6
Dog 6
Horse 1

Breeds Most Affected

Unknown 6
Crossbred Canine/dog 1
Warmblood (unspecified) 1
Dachshund (unspecified) 1
Spaniel - King Charles Cavalier 1
Collie - Border 1
Shepherd Dog - German 1
Terrier (unspecified) 1

Associated Drugs

Ceftiofur Crystalline Free Acid 2
Melarsomine Dihydrochloride Injection 2
Ivermectin + Pyrantel As Pamoate Salt 2
Afoxolaner 2
Tylosin 1
Phenylbutazone 1
Recombitek C4 - 13D1.R1 1
Tilmicosin 1
Escitalopram 1
Imrab 3 Tf - 1905.23 1
Enrofloxacin 1
Recombitek C8 - 47K9.R0 1
Melarsomine Dihydrochloride 1
Insulin Injectable Vial 1
Tigilanol Tiglate 1

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Injection site paraesthesia (#2358 of 2,481 by report volume); death-coded 0.0%. PlainBreed reaction plate · report volume stamp 13 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →