Reaction profile

The FDA adverse-event record for pyothorax

Name: Pyothorax - FDA Animal Adverse Reaction
Creator: PlainBreed
License: https://open.fda.gov/license/

15 FDA reports name pyothorax, a lower-volume reaction in the CVM extract (VeDDRA 893). Plate stamps and neighbourhood peers follow.

#2312 of 2,481
by report volume (all reactions): 15
reports citing this reaction: 73.3%
death-coded share: Dog
most-affected species

Compiled by PlainBreed

Verify with FDA CVM →

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Pyothorax has 15 reports now versus 15 in that prior snapshot: 0 the same number of (0.0%).

Report change: +0
Death-coded reports: +0
Death-coded share: +0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Pyothorax changes

FDA AER · VeDDRA plate

Code 893 VOL-TRACE

VOL-TRACE · DEATH-HOT · BOTTOM-DECILE · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

VOL-TRACE 15 reports
DEATH-HOT 73.3%
BOTTOM-DECILE #2312/2481
PHOTO-FINISH Abomasal ulcer
SPECIES-DOG Dog · 11
DRUG-LEAD Enrofloxacin · 6
DESK-WIDE 12 breeds
BOOK-FULL 8/8 fields

Nearest volume peer: Abomasal ulcer (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Lower-volume neighbourhood around Pyothorax

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

FDA AER report volume · neighbourhood around Pyothorax

Pyothorax: high death-coded share in the FDA AER plate

Signature read: Pyothorax's 73.3% death-coded share is among the highest in the openFDA reaction corpus. Report volume is lower-third scale: 15 named reports in the openFDA extract. Death-coded share is upper-third: 11 of 15 reports (73.3% of named reports). Nearest volume peer: Abomasal ulcer (±0 reports). Lead species Dog (11). Lead co-reported drug Enrofloxacin (6).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 11

Cat 3

Cattle 1

Breeds Most Affected

Domestic Shorthair 2

Newfoundland 2

Bulldog - French 2

Poodle - Miniature 1

Mixed (Cattle) 1

Pug 1

Dogue de Bordeaux 1

Boxer (German Boxer) 1

Poodle - Standard 1

Retriever - Golden 1

Associated Drugs

Enrofloxacin 6

Oclacitinib Maleate 5

Milbemycin Oxime + Spinosad 2

Cyclosporine 2

Meloxicam 2

Maropitant Citrate 2

Hydroxyzine 2

Glucosamine 2

Fish Oil 2

Chinese Herbs 2

Carprofen 2

Methadone 2

Omeprazole 2

Gabapentin 2

Veterinary Diet 2

Prednisone 2

Clindamycin 2

Dexamethasone Sodium Phosphate 2

Amoxicillin + Potassium Clavulanate 2

Diphenhydramine 2

What to do with this reaction

Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
Browse the full reaction directory to compare report counts across reaction types. All reactions

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Pyothorax (#2312 of 2,481 by report volume); death-coded 73.3%. PlainBreed reaction plate · death-coded share stamp 73.3% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →