Reaction profile

The FDA adverse-event record for epileptic fit

11 FDA adverse-event reports reference epileptic fit (VeDDRA 1443). See the species, breeds, and drugs most associated with it below.

11
reports citing this reaction
18.2%
death-coded share
Dog
most-affected species
Afoxolaner 136 Mg Chewable Tablets
most-associated drug
Verify with FDA CVM →
11
Total Reports
2
Deaths
18.2%
Death Rate

Species Most Affected

Dog 10
Cat 1

Breeds Most Affected

Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog) 2
Crossbred Canine/dog 2
Chartreuse 1
Spaniel (unspecified) 1
Unknown 1
Terrier - Jack Russell 1
Doberman Pinscher 1
Terrier (unspecified) 1
Coonhound - Bluetick 1

Associated Drugs

Afoxolaner 136 Mg Chewable Tablets 3
Deracoxib 1
Amoxicillin 1
Gentamicin/ Betamethasone/ Clotrimazole 1
Ivermectin/Pyrantel 1
Dimenhydrinate 1
Ivermectin 1
Afoxolaner 68 Mg Chewable Tablets 1
Afoxolaner 28.3 Mg Chewable Tablets 1
Milbemycin Oxime + Spinosad 1
Alfaxalone 1
Gabapentin 1
Grapiprant 1
Pyrantel Pamoate;Sarolaner 1
Fluralaner 13.64% 12-Week Chew 1

Epileptic fit Reaction Insights

11 reports name Epileptic fit; 2 recorded a death outcome (18.2% of reported events, not a population-level mortality rate). VeDDRA code: 1443.

By species: Dog (10 reports), Cat (1 reports). By breed: Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog) (2), Crossbred Canine/dog (2), Chartreuse (1).

Most co-reported drugs: Afoxolaner 136 Mg Chewable Tablets (3 reports), Deracoxib (1 reports), Amoxicillin (1 reports), Gentamicin/ Betamethasone/ Clotrimazole (1 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.