NT - acute (interstitial) pneumonia/pleuropneumonia

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VeDDRA Code: 2295

32 adverse event reports referencing this reaction

32
Total Reports
24
Deaths
7500.0%
Death Rate

Species Most Affected

Dog 14
Cattle 12
Other Birds 2
Pig 2
Cat 2

Breeds Most Affected

Retriever - Labrador 3
Cattle (unknown) 3
Holstein-Friesian also known as Holstein 2
Cattle (other) 2
Other Birds (other) 2
Mixed (Cattle) 2
Domestic Shorthair 2
Crossbred Bovine/Cattle 2
Jersey 1
Spaniel - Cocker American 1

Associated Drugs

Milbemycin Oxime, Lufenuron 4
Ceftiofur Crystalline Free Acid 3
Meloxicam 3
Tylosin Phosphate 3
Monensin Sodium 3
Moxidectin 3
Bovine Respiratory Syncytial Virus, 597-10 10Th Psg Strain 375; Bovine Viral Dia 2
Tulathromycin 2
Bovine Parainfluenza Virus 3 (Ts), Rlb103 (Nl-Bk-6), Mlv; Bovine Respiratory Syn 2
Trenbolone Acet/Estradiol Impl 2
Tilmicosin 2
Estradiol + Trenbolone 2
Oxfendazole 2
Dinoprost Tromethamine 2
Fluralaner Chew Tablets 2
Melengestrol Acetate 1
Milbemycin Oxime + Spinosad 1
Oclacitinib Maleate 1
Doramectin; Phenol 1
Albendazole 1

Data Summary

Metric Value
Total reports referencing reaction 32
Reports with fatal outcome 24
Case-fatality rate (reported events) 7500.0%
Species observed 5
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 2295.

NT - acute (interstitial) pneumonia/pleuropneumonia Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 32 adverse event reports that reference NT - acute (interstitial) pneumonia/pleuropneumonia as a reaction term, including 24 reports with a death outcome — a 7500.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 2295, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

NT - acute (interstitial) pneumonia/pleuropneumonia appears most frequently in reports for Dog (14 reports), Cattle (12 reports), Other Birds (2 reports) — with Dog dominating at 14 entries. Within those species, the breeds most often named alongside this reaction are Retriever - Labrador (3), Cattle (unknown) (3), Holstein-Friesian also known as Holstein (2). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with NT - acute (interstitial) pneumonia/pleuropneumonia are Milbemycin Oxime, Lufenuron (4 reports), Ceftiofur Crystalline Free Acid (3 reports), Meloxicam (3 reports), Tylosin Phosphate (3 reports), with Milbemycin Oxime, Lufenuron appearing alongside this reaction in 4 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial