Reaction profile

The FDA adverse-event record for third eyelid prolapse

154 FDA adverse-event reports reference third eyelid prolapse (VeDDRA 1104). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1172 of 2,481
by report volume (all reactions)
154
reports citing this reaction
7.8%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Third eyelid prolapse has 154 reports now versus 153 in that prior snapshot: 1 more (0.7%).

Report change
+1
Death-coded reports
+0
Death-coded share
−0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Third eyelid prolapse changes

FDA AER · VeDDRA plate

Code 1104 VOL-LOW

VOL-LOW · DEATH-PAR · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 154 reports
  • DEATH-PAR 7.8%
  • MID-PACK #1172/2481
  • PHOTO-FINISH Folliculitis
  • SPECIES-DOG Dog · 84
  • DRUG-LEAD Milbemycin Oxime… · 26
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Folliculitis (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Third eyelid prolapse

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Folliculitis · near154Lot # and/or Expirati… · near154Neurogenic keratoconj… · near154Third eyelid prolapse · this…154High ionized calcium… · near153Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Third eyelid prolapse

Third eyelid prolapse: low death-coded share in the FDA AER plate

Signature read: Third eyelid prolapse's 7.8% death-coded share is among the lowest in the openFDA reaction corpus. Report volume sits in the middle third of the reaction corpus. Death-coded share is lower-third: 12 of 154 reports (7.8% of named reports). Nearest volume peer: Folliculitis (±0 reports). Lead species Dog (84). Lead co-reported drug Milbemycin Oxime + Spinosad (26).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Milbemycin Oxime + Spinosad appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 84
Cat 69
Horse 1

Breeds Most Affected

Domestic Shorthair 46
Retriever - Labrador 14
Retriever - Golden 9
Domestic Longhair 5
Boxer (German Boxer) 5
Domestic Mediumhair 5
Cat (unknown) 5
Crossbred Canine/dog 4
Spaniel - Cocker American 3
Hound - Basset 3

Associated Drugs

Milbemycin Oxime + Spinosad 26
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 23
Maropitant Citrate 13
Selamectin 7
Oclacitinib Maleate 7
Florfenicol, Terbinafine, Betamethasone Acetate 7
Imidacloprid + Moxidectin 6
Rabies Vaccine 6
Buprenorphine 6
Bedinvetmab 6
Prednisone 5
Spinosad 5
Afoxolaner 5
Milbemycin Oxime + Praziquantel 5
Moxidectin 4
Metronidazole 4
Florfenicol/Terbinafine Hydrochloride/Mometasone Furoate 4
Gabapentin 4
Dexamethasone + Neomycin Sulfate + Thiabendazole 4
Pyrantel Pamoate;Sarolaner 4

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Third eyelid prolapse, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar death-coded share

Nearest other reactions by death-coded share (7.8% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Third eyelid prolapse (#1172 of 2,481 by report volume); death-coded 7.8%. PlainBreed reaction plate · death-coded share stamp 7.8% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →