Reaction profile

The FDA adverse-event record for joint cartilage disorder nos

38 FDA reports name joint cartilage disorder nos, a lower-volume reaction in the CVM extract (VeDDRA 2243). Plate stamps and neighbourhood peers follow.

#1876 of 2,481
by report volume (all reactions)
38
reports citing this reaction
18.4%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Joint cartilage disorder NOS has 38 reports now versus 37 in that prior snapshot: 1 more (2.7%).

Report change
+1
Death-coded reports
+1
Death-coded share
+2.2 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Joint cartilage disorder NOS changes

FDA AER · VeDDRA plate

Code 2243 VOL-TRACE

VOL-TRACE · DEATH-ELEV · LOWER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-TRACE 38 reports
  • DEATH-ELEV 18.4%
  • LOWER-Q #1876/2481
  • PHOTO-FINISH Clenched jaw
  • SPECIES-DOG Dog · 29
  • DRUG-LEAD Carprofen · 9
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Clenched jaw (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Lower-volume neighbourhood around Joint cartilage disorder NOS

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Clenched jaw · near38Conjunctival reddening · near38Disturbance in attent… · near38Duodenitis · near38Joint cartilage disor… · thi…38Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Joint cartilage disorder NOS

What the FDA AER plate says about Joint cartilage disorder NOS

Signature read: 38 reports place Joint cartilage disorder NOS in the lower third of FDA AER volume (#1876 of 2,481). Report volume is lower-third scale: 38 named reports in the openFDA extract. 7 of 38 reports were death-coded (18.4% of named reports, not a population mortality rate). Nearest volume peer: Clenched jaw (±0 reports). Lead species Dog (29). Lead co-reported drug Carprofen (9).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Carprofen appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 29
Horse 6
Human 1
Goat 1
Cat 1

Breeds Most Affected

Retriever - Labrador 3
Terrier - West Highland White 2
Oldenburg 2
Quarter Horse 2
Poodle - Miniature 2
Terrier - Yorkshire 2
Crossbred Canine/dog 2
Siberian Husky 2
Pug 1
Shih Tzu 1

Associated Drugs

Carprofen 9
Bedinvetmab 8
Milbemycin Oxime + Spinosad 4
Oclacitinib Maleate 3
Hyaluronic Acid 3
Fluralaner Chew Tablets 3
Gabapentin 3
Triamcinolone Acetonide 2
Hyaluronate Sodium 2
Milbemycin Oxime 2
Milbemycin Oxime + Praziquantel 2
Insulin Injectable Vial 2
Sarolaner 2
Firocoxib 57 Mg Chewable 1
Selamectin 1
Levothyroxine Sodium 1
Clodronate Disodium 1
Florfenicol Inj Sol 30% W Pg 1
Ivermectin 1
Phenylpropanolamine Hydrochloride 1

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Joint cartilage disorder NOS (#1876 of 2,481 by report volume); death-coded 18.4%. PlainBreed reaction plate · report volume stamp 38 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →