Reaction profile

The FDA adverse-event record for retinal detachment

157 FDA adverse-event reports reference retinal detachment (VeDDRA 465). See the species, breeds, and drugs most associated with it below.

157
reports citing this reaction
20.4%
death-coded share
Dog
most-affected species
Enrofloxacin
most-associated drug
Verify with FDA CVM →
157
Total Reports
32
Deaths
20.4%
Death Rate

Species Most Affected

Dog 94
Cat 63

Breeds Most Affected

Domestic Shorthair 45
Retriever - Labrador 11
Shih Tzu 8
Domestic Longhair 7
Shepherd Dog - German 5
Crossbred Canine/dog 5
Collie - Border 5
Chihuahua 4
Bichon Frise 3
Siamese 3

Associated Drugs

Enrofloxacin 18
Cefovecin 10
Spinosad 9
Frunevetmab 9
Milbemycin Oxime + Spinosad 8
Doxycycline 8
Prednisone 8
Trilostane 7
Orbifloxacin Oral Suspension 7
Maropitant Citrate 7
Meloxicam 6
Carprofen 6
Moxidectin 6
Dexamethasone 5
Cyclosporine 5
Milbemycin Oxime + Praziquantel 5
Ivermectin 4
Deracoxib 4
Oclacitinib Maleate 4
Afoxolaner 4

Retinal detachment Reaction Insights

157 reports name Retinal detachment; 32 recorded a death outcome (20.4% of reported events, not a population-level mortality rate). VeDDRA code: 465.

By species: Dog (94 reports), Cat (63 reports). By breed: Domestic Shorthair (45), Retriever - Labrador (11), Shih Tzu (8).

Most co-reported drugs: Enrofloxacin (18 reports), Cefovecin (10 reports), Spinosad (9 reports), Frunevetmab (9 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.