Reaction profile

The FDA adverse-event record for digestive tract neoplasm nos

118 FDA adverse-event reports reference digestive tract neoplasm nos (VeDDRA 307). See the species, breeds, and drugs most associated with it below.

118
reports citing this reaction
71.2%
death-coded share
Dog
most-affected species
Milbemycin Oxime + Spinosad
most-associated drug
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118
Total Reports
84
Deaths
71.2%
Death Rate

Species Most Affected

Dog 94
Cat 22
Cattle 1
Horse 1

Breeds Most Affected

Retriever - Labrador 11
Dog (unknown) 11
Domestic Shorthair 9
Crossbred Canine/dog 8
Retriever - Golden 6
Beagle 5
Spaniel - Cocker American 4
Chihuahua 4
Domestic Longhair 4
Cat (unknown) 4

Associated Drugs

Milbemycin Oxime + Spinosad 26
Cyclosporine A 13
Oclacitinib Maleate 11
Spinosad 10
Maropitant Citrate 9
Fluralaner Chew Tablets 9
Carprofen 8
Gabapentin 7
Imidacloprid + Moxidectin 6
Ivermectin + Pyrantel As Pamoate Salt 5
Prednisolone 5
Metronidazole 4
Mirtazapine 4
Deracoxib 3
Ivermectin 3
Tramadol 3
Tylosin Tartrate 3
Firocoxib 2
Moxidectin 2
Prednisone 2

Digestive tract neoplasm NOS Reaction Insights

118 reports name Digestive tract neoplasm NOS; 84 recorded a death outcome (71.2% of reported events, not a population-level mortality rate). VeDDRA code: 307.

By species: Dog (94 reports), Cat (22 reports), Cattle (1 reports). By breed: Retriever - Labrador (11), Dog (unknown) (11), Domestic Shorthair (9).

Most co-reported drugs: Milbemycin Oxime + Spinosad (26 reports), Cyclosporine A (13 reports), Oclacitinib Maleate (11 reports), Spinosad (10 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.