Impaired gastric function

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VeDDRA Code: 1894

83 adverse event reports referencing this reaction

83
Total Reports
22
Deaths
2650.0%
Death Rate

Species Most Affected

Dog 62
Horse 12
Cat 6
Human 2
Cattle 1

Breeds Most Affected

Retriever - Labrador 11
Shepherd Dog - German 4
Retriever - Chesapeake Bay 3
Domestic Shorthair 3
Terrier - Yorkshire 3
Shepherd Dog - Australian 3
Retriever (unspecified) 2
Dog (unknown) 2
Cat (unknown) 2
Dachshund (unspecified) 2

Associated Drugs

Maropitant Citrate 22
Milbemycin Oxime + Spinosad 9
Carprofen 7
Meloxicam 6
Deracoxib 6
Trilostane 5
Tramadol 5
Ivermectin 4
Metronidazole 4
Metoclopramide 4
Famotidine 4
Polysulfated Glycosaminoglycan 4
Grapiprant 4
Milbemycin Oxime + Praziquantel 4
Butorphanol 4
Selamectin 3
Fluralaner 3
Ceftiofur Crystalline Free Acid 3
Maropitant 3
Dexmedetomidine 3

Data Summary

Metric Value
Total reports referencing reaction 83
Reports with fatal outcome 22
Case-fatality rate (reported events) 2650.0%
Species observed 5
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 1894.

Impaired gastric function Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 83 adverse event reports that reference Impaired gastric function as a reaction term, including 22 reports with a death outcome — a 2650.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 1894, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Impaired gastric function appears most frequently in reports for Dog (62 reports), Horse (12 reports), Cat (6 reports) — with Dog dominating at 62 entries. Within those species, the breeds most often named alongside this reaction are Retriever - Labrador (11), Shepherd Dog - German (4), Retriever - Chesapeake Bay (3). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Impaired gastric function are Maropitant Citrate (22 reports), Milbemycin Oxime + Spinosad (9 reports), Carprofen (7 reports), Meloxicam (6 reports), with Maropitant Citrate appearing alongside this reaction in 22 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial