Reaction profile

The FDA adverse-event record for impaired gastric function

83 FDA adverse-event reports reference impaired gastric function (VeDDRA 1894). See the species, breeds, and drugs most associated with it below.

83
reports citing this reaction
26.5%
death-coded share
Dog
most-affected species
Maropitant Citrate
most-associated drug
Verify with FDA CVM →
83
Total Reports
22
Deaths
26.5%
Death Rate

Species Most Affected

Dog 62
Horse 12
Cat 6
Human 2
Cattle 1

Breeds Most Affected

Retriever - Labrador 11
Shepherd Dog - German 4
Retriever - Chesapeake Bay 3
Domestic Shorthair 3
Terrier - Yorkshire 3
Shepherd Dog - Australian 3
Retriever (unspecified) 2
Dog (unknown) 2
Cat (unknown) 2
Dachshund (unspecified) 2

Associated Drugs

Maropitant Citrate 22
Milbemycin Oxime + Spinosad 9
Carprofen 7
Meloxicam 6
Deracoxib 6
Trilostane 5
Tramadol 5
Ivermectin 4
Metronidazole 4
Metoclopramide 4
Famotidine 4
Polysulfated Glycosaminoglycan 4
Grapiprant 4
Milbemycin Oxime + Praziquantel 4
Butorphanol 4
Selamectin 3
Fluralaner 3
Ceftiofur Crystalline Free Acid 3
Maropitant 3
Dexmedetomidine 3

Impaired gastric function Reaction Insights

83 reports name Impaired gastric function; 22 recorded a death outcome (26.5% of reported events, not a population-level mortality rate). VeDDRA code: 1894.

By species: Dog (62 reports), Horse (12 reports), Cat (6 reports). By breed: Retriever - Labrador (11), Shepherd Dog - German (4), Retriever - Chesapeake Bay (3).

Most co-reported drugs: Maropitant Citrate (22 reports), Milbemycin Oxime + Spinosad (9 reports), Carprofen (7 reports), Meloxicam (6 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.