Reaction profile

The FDA adverse-event record for injection site alopecia

452 FDA reports name injection site alopecia, a high-volume reaction in the CVM extract (VeDDRA 73). Plate stamps and neighbourhood peers follow.

#678 of 2,481
by report volume (all reactions)
452
reports citing this reaction
2.9%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Injection site alopecia has 452 reports now versus 441 in that prior snapshot: 11 more (2.5%).

Report change
+11
Death-coded reports
+0
Death-coded share
−0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Injection site alopecia changes

FDA AER · VeDDRA plate

Code 73 VOL-LOW

VOL-LOW · DEATH-LOW · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 452 reports
  • DEATH-LOW 2.9%
  • MID-PACK #678/2481
  • PHOTO-FINISH Fungal skin infection…
  • SPECIES-DOG Dog · 230
  • DRUG-LEAD Cefovecin · 62
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Fungal skin infection NOS (±0 reports)

Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Injection site alopecia

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Fungal skin infection… · near452Injection site alopec… · thi…452Low creatinine · near451Eyelid oedema · near450Lack of efficacy (lic… · near450Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Injection site alopecia

Injection site alopecia: low death-coded share in the FDA AER plate

Signature read: Injection site alopecia's 2.9% death-coded share is among the lowest in the openFDA reaction corpus. Report volume is upper-third scale: 452 named reports in the openFDA extract. Death-coded share is lower-third: 13 of 452 reports (2.9% of named reports). Nearest volume peer: Fungal skin infection NOS (±0 reports). Lead species Dog (230). Lead co-reported drug Cefovecin (62).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Cefovecin appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 230
Cat 184
Horse 20
Cattle 13
Mouse 2
Sheep 1
Rat 1
Ferret 1

Breeds Most Affected

Domestic Shorthair 105
Domestic (unspecified) 29
Crossbred Canine/dog 19
Retriever - Labrador 18
Chihuahua 15
Shih Tzu 13
Retriever - Golden 11
Domestic Longhair 10
Boxer (German Boxer) 9
Terrier - Bull - American Pit 8

Associated Drugs

Cefovecin 62
Carprofen 47
Frunevetmab 36
Maropitant Citrate 33
Prednisone 32
Moxidectin 31
Meloxicam 27
Praziquantel 26
Cefovecin Sodium 24
Enrofloxacin 22
Gabapentin 22
Tigilanol Tiglate 20
Diphenhydramine 19
Famotidine 18
Bedinvetmab 18
Selamectin 17
Robenacoxib 17
Buprenorphine 15
Methylprednisolone Acetate 14
Rabies Vaccine, Killed Virus 14

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Injection site alopecia, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (452 here).

Similar death-coded share

Nearest other reactions by death-coded share (2.9% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Injection site alopecia (#678 of 2,481 by report volume); death-coded 2.9%. PlainBreed reaction plate · death-coded share stamp 2.9% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →