Reaction profile

The FDA adverse-event record for injection site alopecia

428 FDA adverse-event reports reference injection site alopecia (VeDDRA 73). See the species, breeds, and drugs most associated with it below.

428
reports citing this reaction
2.8%
death-coded share
Dog
most-affected species
Cefovecin
most-associated drug
Verify with FDA CVM →
428
Total Reports
12
Deaths
2.8%
Death Rate

Species Most Affected

Dog 213
Cat 178
Horse 19
Cattle 13
Mouse 2
Sheep 1
Rat 1
Ferret 1

Breeds Most Affected

Domestic Shorthair 101
Domestic (unspecified) 29
Retriever - Labrador 17
Crossbred Canine/dog 16
Chihuahua 14
Shih Tzu 12
Domestic Longhair 10
Retriever - Golden 10
Boxer (German Boxer) 9
Domestic Mediumhair 7

Associated Drugs

Cefovecin 61
Carprofen 43
Frunevetmab 34
Prednisone 32
Moxidectin 30
Maropitant Citrate 30
Praziquantel 26
Cefovecin Sodium 24
Meloxicam 24
Enrofloxacin 20
Famotidine 18
Diphenhydramine 18
Selamectin 17
Gabapentin 17
Tigilanol Tiglate 16
Bedinvetmab 15
Buprenorphine 14
Robenacoxib 14
Rabies Vaccine, Killed Virus 13
Methylprednisolone Acetate 12

Injection site alopecia Reaction Insights

428 reports name Injection site alopecia; 12 recorded a death outcome (2.8% of reported events, not a population-level mortality rate). VeDDRA code: 73.

By species: Dog (213 reports), Cat (178 reports), Horse (19 reports). By breed: Domestic Shorthair (101), Domestic (unspecified) (29), Retriever - Labrador (17).

Most co-reported drugs: Cefovecin (61 reports), Carprofen (43 reports), Frunevetmab (34 reports), Prednisone (32 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.