Reaction profile

The FDA adverse-event record for application site abscess

46 FDA adverse-event reports reference application site abscess (VeDDRA 2004). See the species, breeds, and drugs most associated with it below.

46
reports citing this reaction
6.5%
death-coded share
Cat
most-affected species
Selamectin
most-associated drug
Verify with FDA CVM →
46
Total Reports
3
Deaths
6.5%
Death Rate

Species Most Affected

Cat 17
Dog 15
Cattle 8
Horse 6

Breeds Most Affected

Domestic Shorthair 14
Quarter Horse 4
Shepherd Dog - German 2
Bloodhound 2
Retriever - Labrador 2
Holstein-Friesian also known as Holstein 2
Cattle (other) 2
Siamese 2
Aberdeen Angus 2
Chihuahua 2

Associated Drugs

Selamectin 8
Chlorpheniramine 4
Triple Antibiotic Ointment (Ophthalmic) 4
Imidacloprid + Moxidectin 3
Emodepside + Praziquantel 3
Ivermectin(1.55%)/Praziquantel(7.75%) Paste 3
Selamectin;Sarolaner 3
Fluralaner Spot-On Solution 3
Cefovecin Sodium 3
Pain Meds (Unknown) 3
Orbifloxacin 3
Famciclovir 3
Praziquantel 2
Polysulfated Glycosaminoglycan 2
Ivermectin/Pyrantel Pamoate Chewable 272Mcg/652Mg 2
Fipronil 10%/S Methoprene 9% Spot On 2
Ceftiofur Crystalline Free Acid 2
Progesterone 2
Eprinomectin 2
Cefovecin 2

Application site abscess Reaction Insights

46 reports name Application site abscess; 3 recorded a death outcome (6.5% of reported events, not a population-level mortality rate). VeDDRA code: 2004.

By species: Cat (17 reports), Dog (15 reports), Cattle (8 reports). By breed: Domestic Shorthair (14), Quarter Horse (4), Shepherd Dog - German (2).

Most co-reported drugs: Selamectin (8 reports), Chlorpheniramine (4 reports), Triple Antibiotic Ointment (Ophthalmic) (4 reports), Imidacloprid + Moxidectin (3 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.