Reaction profile

The FDA adverse-event record for application site abscess

48 FDA reports name application site abscess, a lower-volume reaction in the CVM extract (VeDDRA 2004). Plate stamps and neighbourhood peers follow.

#1754 of 2,481
by report volume (all reactions)
48
reports citing this reaction
6.3%
death-coded share
Cat
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Application site abscess has 48 reports now versus 46 in that prior snapshot: 2 more (4.3%).

Report change
+2
Death-coded reports
+0
Death-coded share
−0.3 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Application site abscess changes

FDA AER · VeDDRA plate

Code 2004 VOL-TRACE

VOL-TRACE · DEATH-PAR · MID-PACK · PHOTO-FINISH · SPECIES-CAT · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-TRACE 48 reports
  • DEATH-PAR 6.3%
  • MID-PACK #1754/2481
  • PHOTO-FINISH Abnormal echocardiogr…
  • SPECIES-CAT Cat · 18
  • DRUG-LEAD Selamectin · 8
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Abnormal echocardiogram (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Lower-volume neighbourhood around Application site abscess

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Abnormal echocardiogr… · near48Application site absc… · thi…48Brain damage NOS · near48Brain tumour · near48Infarction · near48Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Application site abscess

Application site abscess: low death-coded share in the FDA AER plate

Signature read: 3 death-coded reports is a thin tail count for Application site abscess in the CVM extract. Report volume is lower-third scale: 48 named reports in the openFDA extract. Death-coded share is lower-third: 3 of 48 reports (6.3% of named reports). Nearest volume peer: Abnormal echocardiogram (±0 reports). Lead species Cat (18). Lead co-reported drug Selamectin (8).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Selamectin appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Cat 18
Dog 15
Cattle 8
Horse 7

Breeds Most Affected

Domestic Shorthair 15
Quarter Horse 5
Shepherd Dog - German 2
Bloodhound 2
Retriever - Labrador 2
Holstein-Friesian also known as Holstein 2
Cattle (other) 2
Siamese 2
Aberdeen Angus 2
Chihuahua 2

Associated Drugs

Selamectin 8
Chlorpheniramine 4
Triple Antibiotic Ointment (Ophthalmic) 4
Imidacloprid + Moxidectin 3
Emodepside + Praziquantel 3
Ivermectin(1.55%)/Praziquantel(7.75%) Paste 3
Selamectin;Sarolaner 3
Fluralaner Spot-On Solution 3
Cefovecin Sodium 3
Ketamine 3
Pain Meds (Unknown) 3
Orbifloxacin 3
Famciclovir 3
Praziquantel 2
Polysulfated Glycosaminoglycan 2
Ivermectin/Pyrantel Pamoate Chewable 272Mcg/652Mg 2
Fipronil 10%/S Methoprene 9% Spot On 2
Progesterone 2
Ceftiofur Crystalline Free Acid 2
Eprinomectin 2

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Application site abscess (#1754 of 2,481 by report volume); death-coded 6.3%. PlainBreed reaction plate · death-coded report count stamp 3 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →