Reaction profile

The FDA adverse-event record for pawing

324 FDA adverse-event reports reference pawing (VeDDRA 2592). See the species, breeds, and drugs most associated with it below.

324
reports citing this reaction
4.6%
death-coded share
Dog
most-affected species
Moxidectin
most-associated drug
Verify with FDA CVM →
324
Total Reports
15
Deaths
4.6%
Death Rate

Species Most Affected

Dog 181
Horse 79
Cat 62
Cattle 2

Breeds Most Affected

Domestic Shorthair 37
Quarter Horse 20
Chihuahua 13
Retriever - Golden 11
Retriever - Labrador 11
Thoroughbred 9
Horse (unknown) 8
Cat (unknown) 8
Warmblood (unspecified) 7
Spaniel - King Charles Cavalier 7

Associated Drugs

Moxidectin 30
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 28
Clodronate Disodium 24
Afoxolaner 14
Ceftiofur Crystalline Free Acid 14
Maropitant Citrate 12
Buprenorphine 12
Fluralaner Spot-On Solution 11
Pyrantel Pamoate;Sarolaner 11
Carprofen 10
Selamectin 9
Fluralaner 13.64% 12-Week Chew 9
Bordetella Vaccine 8
Firocoxib 7
Sarolaner 7
Mirtazapine 7
Polysulfated Glycosaminoglycan 7
Phenylbutazone 6
Fluralaner Chew Tablets 6
Ivermectin + Praziquantel 6

Pawing Reaction Insights

324 reports name Pawing; 15 recorded a death outcome (4.6% of reported events, not a population-level mortality rate). VeDDRA code: 2592.

By species: Dog (181 reports), Horse (79 reports), Cat (62 reports). By breed: Domestic Shorthair (37), Quarter Horse (20), Chihuahua (13).

Most co-reported drugs: Moxidectin (30 reports), Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride (28 reports), Clodronate Disodium (24 reports), Afoxolaner (14 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.