Reaction profile

The FDA adverse-event record for tendon injury

33 FDA adverse-event reports reference tendon injury (VeDDRA 626). See the species, breeds, and drugs most associated with it below.

33
reports citing this reaction
6.1%
death-coded share
Dog
most-affected species
Tigilanol Tiglate
most-associated drug
Verify with FDA CVM →
33
Total Reports
2
Deaths
6.1%
Death Rate

Species Most Affected

Dog 25
Horse 4
Cat 4

Breeds Most Affected

Retriever - Labrador 6
Crossbred Canine/dog 4
Quarter Horse 2
Shepherd Dog - German 2
Dog (unknown) 2
Bulldog 1
Newfoundland 1
Horse (unknown) 1
Warmblood - Dutch 1
Papillon - Spaniel - Continental Toy (with erect ears or with dropped ears (Phaléne)) 1

Associated Drugs

Tigilanol Tiglate 9
Gabapentin 4
Frunevetmab 4
Bedinvetmab 4
Enrofloxacin 2
Milbemycin Oxime + Spinosad 2
Ceftiofur 2
Dexamethasone 2
Trilostane 2
Deracoxib 2
Clodronate Disodium 2
Carprofen 2
Cosequin 2
Pimobendan 2
Methocarbamol 2
Rabies Vaccine 1
Distemper Vaccine 1
Bordetella Vaccine 1
Clindamycin 1
Device: Tissue Adhesive 1

Tendon injury Reaction Insights

33 reports name Tendon injury; 2 recorded a death outcome (6.1% of reported events, not a population-level mortality rate). VeDDRA code: 626.

By species: Dog (25 reports), Horse (4 reports), Cat (4 reports). By breed: Retriever - Labrador (6), Crossbred Canine/dog (4), Quarter Horse (2).

Most co-reported drugs: Tigilanol Tiglate (9 reports), Gabapentin (4 reports), Frunevetmab (4 reports), Bedinvetmab (4 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.