Reaction profile

The FDA adverse-event record for pulmonary fibrosis

51 FDA reports name pulmonary fibrosis, a lower-volume reaction in the CVM extract (VeDDRA 2259). Plate stamps and neighbourhood peers follow.

#1731 of 2,481
by report volume (all reactions)
51
reports citing this reaction
80.4%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Pulmonary fibrosis has 51 reports now versus 49 in that prior snapshot: 2 more (4.1%).

Report change
+2
Death-coded reports
+2
Death-coded share
+0.8 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Pulmonary fibrosis changes

FDA AER · VeDDRA plate

Code 2259 VOL-LOW

VOL-LOW · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 51 reports
  • DEATH-HOT 80.4%
  • MID-PACK #1731/2481
  • PHOTO-FINISH Application site scar
  • SPECIES-DOG Dog · 42
  • DRUG-LEAD Rabacfosadine · 14
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Application site scar (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Lower-volume neighbourhood around Pulmonary fibrosis

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Application site scar · near51Chest discomfort NOS · near51Drug administration d… · near51Dystocia · near51Pulmonary fibrosis · this re…51Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Pulmonary fibrosis

Pulmonary fibrosis: high death-coded share in the FDA AER plate

Signature read: Pulmonary fibrosis's 80.4% death-coded share is among the highest in the openFDA reaction corpus. Report volume is lower-third scale: 51 named reports in the openFDA extract. Death-coded share is upper-third: 41 of 51 reports (80.4% of named reports). Nearest volume peer: Application site scar (±0 reports). Lead species Dog (42). Lead co-reported drug Rabacfosadine (14).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 42
Cat 6
Cattle 3

Breeds Most Affected

Retriever - Golden 5
Crossbred Canine/dog 5
Retriever - Labrador 5
Domestic Shorthair 4
Cattle (unknown) 3
Coton de Tuléar 3
Shih Tzu 2
Spaniel - Cocker American 2
Terrier - Yorkshire 2
Pit Bull 2

Associated Drugs

Rabacfosadine 14
Rabacfosadine Succinate 8
Maropitant 7
Enrofloxacin 7
Prednisone 6
Gabapentin 6
Fluid Therapy 5
Robenacoxib 5
Fluralaner 4
Cefovecin Sodium 4
Oclacitinib Maleate 4
Grapiprant 4
Buprenorphine 4
Trenbolone; Estradiol; Tylosin Tartrate 3
Flunixin Meglumine 3
Escherichia Coli K99 Antibody 3
Isoflurane 3
Mirtazapine 3
Rattlesnake Vaccine 3
Metoclopramide 3

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Pulmonary fibrosis, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (51 here).

Similar death-coded share

Nearest other reactions by death-coded share (80.4% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Pulmonary fibrosis (#1731 of 2,481 by report volume); death-coded 80.4%. PlainBreed reaction plate · death-coded share stamp 80.4% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →