Reaction profile

The FDA adverse-event record for low liver enzymes nos

19 FDA reports name low liver enzymes nos, a lower-volume reaction in the CVM extract (VeDDRA 2689). Plate stamps and neighbourhood peers follow.

#2187 of 2,481
by report volume (all reactions)
19
reports citing this reaction
15.8%
death-coded share
Cat
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Low liver enzymes NOS has 19 reports now versus 16 in that prior snapshot: 3 more (18.8%).

Report change
+3
Death-coded reports
+1
Death-coded share
+3.3 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Low liver enzymes NOS changes

FDA AER · VeDDRA plate

Code 2689 VOL-TRACE

VOL-TRACE · DEATH-ELEV · LOWER-Q · PHOTO-FINISH · SPECIES-CAT · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-TRACE 19 reports
  • DEATH-ELEV 15.8%
  • LOWER-Q #2187/2481
  • PHOTO-FINISH Adaptor, damaged
  • SPECIES-CAT Cat · 9
  • DRUG-LEAD Robenacoxib · 8
  • DESK-WIDE 12 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Adaptor, damaged (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Lower-volume neighbourhood around Low liver enzymes NOS

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Adaptor, damaged · near19Amaurosis (see also P… · near19Anhidrosis · near19Cholelithiasis · near19Low liver enzymes NOS · this…19Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Low liver enzymes NOS

What the FDA AER plate says about Low liver enzymes NOS

Signature read: 19 reports place Low liver enzymes NOS in the lower third of FDA AER volume (#2187 of 2,481). Report volume is lower-third scale: 19 named reports in the openFDA extract. 3 of 19 reports were death-coded (15.8% of named reports, not a population mortality rate). Nearest volume peer: Adaptor, damaged (±0 reports). Lead species Cat (9). Lead co-reported drug Robenacoxib (8).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Robenacoxib appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Cat 9
Dog 8
Horse 2

Breeds Most Affected

Domestic Shorthair 5
Spaniel - King Charles Cavalier 2
Schnauzer (unspecified) 2
Domestic Longhair 2
Ragdoll 1
Domestic Mediumhair 1
Terrier - Yorkshire 1
Ridgeback - Rhodesian 1
Dog (unknown) 1
Warmblood (unspecified) 1

Associated Drugs

Robenacoxib 8
Diphenhydramine 8
Prednisolone 5
Maropitant Citrate 4
Feline Rhinotracheitis-Calici-Panleukopenia Vaccine, Killed Virus 4
Rabies Vaccine 4
Famotidine 4
Fluid Therapy 4
Doxycycline 4
Dexamethasone Sodium Phosphate 4
Trilostane 3
Milbemycin Oxime + Praziquantel 2
Bexagliflozin 2
Omeprazole 37% Oral Paste 2
Meloxicam 1
Chlamydia Psittaci,905,Killed + Feline Calicivirus,F-9,Live + Feline Panleukopenia Virus,Johnson Leopard Origin,Live + Feline Rhinotracheitis Virus,F2,Live + Rabies Virus,Vcp65A,Rentschler,Vector 1
Fluralaner 1
Fluralaner 13.64% 12-Week Chew 1
Milbemycin Oxime, Praziquantel 1
Frunevetmab 1

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Low liver enzymes NOS (#2187 of 2,481 by report volume); death-coded 15.8%. PlainBreed reaction plate · report volume stamp 19 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →