Increased band neutrophilia

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VeDDRA Code: 2859

132 adverse event reports referencing this reaction

132
Total Reports
37
Deaths
2800.0%
Death Rate

Species Most Affected

Dog 120
Cat 11
Horse 1

Breeds Most Affected

Retriever - Labrador 18
Crossbred Canine/dog 11
Chihuahua 8
Spaniel - King Charles Cavalier 6
Shepherd Dog - German 5
Terrier - Bull - American Pit 5
Terrier (unspecified) 4
Bulldog - French 4
Domestic Shorthair 4
Bichon Frise 4

Associated Drugs

Carprofen 33
Gabapentin 26
Bedinvetmab 25
Maropitant Citrate 22
Prednisone 15
Trazodone 15
Omeprazole 15
Oclacitinib Maleate 14
Enrofloxacin 13
Metronidazole 11
Maropitant 10
Diphenhydramine 10
Buprenorphine 9
Propofol 9
Moxidectin 9
Pyrantel Pamoate;Sarolaner 8
Ondansetron 8
Midazolam 8
Verdinexor 7
Famotidine 7

Data Summary

Metric Value
Total reports referencing reaction 132
Reports with fatal outcome 37
Case-fatality rate (reported events) 2800.0%
Species observed 3
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 2859.

Increased band neutrophilia Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 132 adverse event reports that reference Increased band neutrophilia as a reaction term, including 37 reports with a death outcome — a 2800.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 2859, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Increased band neutrophilia appears most frequently in reports for Dog (120 reports), Cat (11 reports), Horse (1 reports) — with Dog dominating at 120 entries. Within those species, the breeds most often named alongside this reaction are Retriever - Labrador (18), Crossbred Canine/dog (11), Chihuahua (8). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Increased band neutrophilia are Carprofen (33 reports), Gabapentin (26 reports), Bedinvetmab (25 reports), Maropitant Citrate (22 reports), with Carprofen appearing alongside this reaction in 33 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial