Moribund

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VeDDRA Code: 1040

126 adverse event reports referencing this reaction

126
Total Reports
105
Deaths
8330.0%
Death Rate

Species Most Affected

Dog 58
Fish 24
Cat 18
Cattle 11
Chicken 5
Horse 3
Pig 3
Turtle 1
Turkey 1
Sheep 1

Breeds Most Affected

Atlantic Salmon (Salmo salar) 24
Domestic Shorthair 11
Retriever - Labrador 10
Crossbred Canine/dog 5
Holstein-Friesian also known as Holstein 4
Retriever - Golden 3
Cat (unknown) 3
Chihuahua 3
Terrier - Yorkshire 3
Dachshund (unspecified) 3

Associated Drugs

Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) 24
Maropitant Citrate 8
Carprofen 6
Spinosad 6
Cefovecin 6
Milbemycin Oxime + Spinosad 5
Moxidectin 5
Deracoxib 4
Meloxicam 4
Trilostane 4
Dinoprost Tromethamine 4
Monensin Sodium 4
Fluralaner 13.64% 12-Week Chew 4
Narasin 3
Fenbendazole 3
Enrofloxacin 3
Diphenhydramine Hcl 3
Doxycycline 3
Prednisone 3
Dexamethasone 3

Data Summary

Metric Value
Total reports referencing reaction 126
Reports with fatal outcome 105
Case-fatality rate (reported events) 8330.0%
Species observed 10
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 1040.

Moribund Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 126 adverse event reports that reference Moribund as a reaction term, including 105 reports with a death outcome — a 8330.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 1040, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Moribund appears most frequently in reports for Dog (58 reports), Fish (24 reports), Cat (18 reports) — with Dog dominating at 58 entries. Within those species, the breeds most often named alongside this reaction are Atlantic Salmon (Salmo salar) (24), Domestic Shorthair (11), Retriever - Labrador (10). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Moribund are Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) (24 reports), Maropitant Citrate (8 reports), Carprofen (6 reports), Spinosad (6 reports), with Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) appearing alongside this reaction in 24 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial