Reaction profile

The FDA adverse-event record for low amylase

36 FDA reports name low amylase, a lower-volume reaction in the CVM extract (VeDDRA 3194). Plate stamps and neighbourhood peers follow.

#1912 of 2,481
by report volume (all reactions)
36
reports citing this reaction
27.8%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Low amylase has 36 reports now versus 22 in that prior snapshot: 14 more (63.6%).

Report change
+14
Death-coded reports
+4
Death-coded share
+0.5 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Low amylase changes

FDA AER · VeDDRA plate

Code 3194 VOL-TRACE

VOL-TRACE · DEATH-HOT · LOWER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-TRACE 36 reports
  • DEATH-HOT 27.8%
  • LOWER-Q #1912/2481
  • PHOTO-FINISH Abnormal birth weight
  • SPECIES-DOG Dog · 29
  • DRUG-LEAD Maropitant Citrate · 14
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Abnormal birth weight (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Lower-volume neighbourhood around Low amylase

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Abnormal birth weight · near36Adaptor, leaking · near36Blood dyscrasia NOS · near36Contact dermatitis · near36Low amylase · this reaction36Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Low amylase

Low amylase: high death-coded share in the FDA AER plate

Signature read: 36 reports place Low amylase in the lower third of FDA AER volume (#1912 of 2,481). Report volume is lower-third scale: 36 named reports in the openFDA extract. Death-coded share is upper-third: 10 of 36 reports (27.8% of named reports). Nearest volume peer: Abnormal birth weight (±0 reports). Lead species Dog (29). Lead co-reported drug Maropitant Citrate (14).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 29
Cat 7

Breeds Most Affected

Domestic Shorthair 6
Crossbred Canine/dog 4
Retriever - Labrador 3
Shih Tzu 2
Terrier - Rat 2
Doberman Pinscher 2
Dachshund - Miniature 1
Poodle - Miniature 1
Boxer (German Boxer) 1
Sheepdog (unspecified) 1

Associated Drugs

Maropitant Citrate 14
Carprofen 9
Dexamethasone Sodium Phosphate 5
S-Adenosylmethionine + Silybin 4
Fluralaner 4
Famotidine 4
Capromorelin 4
Bordetella Bronchiseptica, Boehringer Ingelheim Strain 4
Ondansetron 4
Moxidectin 3
Fluralaner Powder For Inj Susp 3
Prednisone 3
Flu Vaccine (Unknown) 3
Dextromethorphan + Guaifenisen 3
Anti-Il31 Mab Mcs Lot #1283563 3
Eprinomectin + Esafoxolaner + Praziquantel 3
Metronidazole 3
Rabies Vaccine 3
Pantoprazole 3
Ampicillin Sodium/Sulbactam Sodium 3

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Low amylase (#1912 of 2,481 by report volume); death-coded 27.8%. PlainBreed reaction plate · report volume stamp 36 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →