Reaction profile

The FDA adverse-event record for mammary gland disorder nos

177 FDA adverse-event reports reference mammary gland disorder nos (VeDDRA 527). See the species, breeds, and drugs most associated with it below.

177
reports citing this reaction
20.3%
death-coded share
Cattle
most-affected species
Sometribove
most-associated drug
Verify with FDA CVM →
177
Total Reports
36
Deaths
20.3%
Death Rate

Species Most Affected

Cattle 79
Dog 77
Horse 13
Cat 7
Goat 1

Breeds Most Affected

Holstein-Friesian also known as Holstein 43
Shepherd Dog - German 9
Mixed (Cattle) 8
Cattle (unknown) 7
Retriever - Labrador 7
Chihuahua 6
Quarter Horse 6
Crossbred Bovine/Cattle 5
Pit Bull 5
Domestic Shorthair 4

Associated Drugs

Sometribove 20
Oclacitinib Maleate 20
Monensin Sodium 14
Altrenogest Oily Solution 11
Cloxacillin Benz Intramam Dc 10
Milbemycin Oxime + Spinosad 9
Estriol Tablets 9
Carprofen 6
Estradiol 5
Fluralaner Chew Tablets 5
Bordetella Vaccine 4
Cephapirin Benzathine 3
Sometribove Zinc Suspension 3
Spinosad 3
Cefpodoxime Proxetil 3
Trenbolone Acet/Estradiol Impl 3
Cefpodoxime 3
Milbemycin Oxime + Praziquantel 3
Progesterone;Estradiol Benzoate 3
Trenbolone Acetate;Estradiol Benzoate 3

Mammary gland disorder NOS Reaction Insights

177 reports name Mammary gland disorder NOS; 36 recorded a death outcome (20.3% of reported events, not a population-level mortality rate). VeDDRA code: 527.

By species: Cattle (79 reports), Dog (77 reports), Horse (13 reports). By breed: Holstein-Friesian also known as Holstein (43), Shepherd Dog - German (9), Mixed (Cattle) (8).

Most co-reported drugs: Sometribove (20 reports), Oclacitinib Maleate (20 reports), Monensin Sodium (14 reports), Altrenogest Oily Solution (11 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.