Reaction profile

The FDA adverse-event record for fluid in thorax

176 FDA adverse-event reports reference fluid in thorax (VeDDRA 1183). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1102 of 2,481
by report volume (all reactions)
176
reports citing this reaction
65.3%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Fluid in thorax has 176 reports now versus 175 in that prior snapshot: 1 more (0.6%).

Report change
+1
Death-coded reports
+0
Death-coded share
−0.4 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Fluid in thorax changes

FDA AER · VeDDRA plate

Code 1183 VOL-LOW

VOL-LOW · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 176 reports
  • DEATH-HOT 65.3%
  • MID-PACK #1102/2481
  • PHOTO-FINISH Agonal breathing
  • SPECIES-DOG Dog · 121
  • DRUG-LEAD Milbemycin Oxime… · 19
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Agonal breathing (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Report-volume neighbourhood around Fluid in thorax

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Agonal breathing · near176Ear canal disorder · near176Fluid in thorax · this react…176Gastric distension · near176Lack of awareness · near176Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Fluid in thorax

Fluid in thorax: high death-coded share in the FDA AER plate

Signature read: Fluid in thorax's 65.3% death-coded share is among the highest in the openFDA reaction corpus. Report volume sits in the middle third of the reaction corpus. Death-coded share is upper-third: 115 of 176 reports (65.3% of named reports). Nearest volume peer: Agonal breathing (±0 reports). Lead species Dog (121). Lead co-reported drug Milbemycin Oxime + Spinosad (19).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 121
Cat 40
Cattle 13
Rabbit 1
Pig 1

Breeds Most Affected

Domestic Shorthair 26
Retriever - Labrador 11
Chihuahua 7
Retriever - Golden 7
Shepherd Dog - German 6
Shepherd Dog - Australian 5
Crossbred Canine/dog 5
Domestic Longhair 5
Bulldog - French 5
Holstein-Friesian also known as Holstein 4

Associated Drugs

Milbemycin Oxime + Spinosad 19
Furosemide 17
Cefovecin 14
Carprofen 13
Prednisone 13
Moxidectin 12
Afoxolaner 11
Spinosad 10
Trilostane 10
Oclacitinib Maleate 9
Maropitant Citrate 9
Gabapentin 8
Antibiotic 8
Monensin Sodium 7
Doxycycline 7
Imidacloprid + Moxidectin 6
Pimobendan 6
Fluralaner 13.64% 12-Week Chew 6
Famotidine 6
Dexamethasone 5

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Fluid in thorax, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (176 here).

Similar death-coded share

Nearest other reactions by death-coded share (65.3% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Fluid in thorax (#1102 of 2,481 by report volume); death-coded 65.3%. PlainBreed reaction plate · death-coded share stamp 65.3% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →