Reaction profile

The FDA adverse-event record for pinnal irritation

137 FDA adverse-event reports reference pinnal irritation (VeDDRA 361). See the species, breeds, and drugs most associated with it below.

137
reports citing this reaction
2.9%
death-coded share
Dog
most-affected species
Prednisone
most-associated drug
Verify with FDA CVM →
137
Total Reports
4
Deaths
2.9%
Death Rate

Species Most Affected

Dog 119
Cat 17
Horse 1

Breeds Most Affected

Retriever - Labrador 17
Crossbred Canine/dog 15
Retriever - Golden 15
Domestic Shorthair 8
Dog (unknown) 6
Shih Tzu 5
Boxer (German Boxer) 4
Pit Bull 4
Beagle 4
Chihuahua 4

Associated Drugs

Prednisone 10
Dexamethasone, Neomycin, Thiabendazole 9
Milbemycin Oxime + Spinosad 9
Genta/Momet/Clotrim Ear Oint 9
Afoxolaner 7
Tresaderm Dermatological Solution 7
Diphenhydramine 6
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 6
Cefovecin 5
Genta/Betamet/Clotrim Ear Oint 5
Carprofen 4
Hydroxyzine 4
Imidacloprid + Moxidectin 4
Cyclosporine 3
Selamectin 3
Ivermectin/Pyrantel Pamoate Chewable 68Mcg/163Mg 3
Gentamicin Sulfate, Hydrocortisone Aceponate, Miconazole Nitrate 3
Maropitant Citrate 3
Miconazole Nitrate + Polymyxin B Sulfate + Prednisolone Acetate 3
Rabies Vaccine 3

Pinnal irritation Reaction Insights

137 reports name Pinnal irritation; 4 recorded a death outcome (2.9% of reported events, not a population-level mortality rate). VeDDRA code: 361.

By species: Dog (119 reports), Cat (17 reports), Horse (1 reports). By breed: Retriever - Labrador (17), Crossbred Canine/dog (15), Retriever - Golden (15).

Most co-reported drugs: Prednisone (10 reports), Dexamethasone, Neomycin, Thiabendazole (9 reports), Milbemycin Oxime + Spinosad (9 reports), Genta/Momet/Clotrim Ear Oint (9 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.