Reaction profile

The FDA adverse-event record for focal seizure

404 FDA reports name focal seizure, a high-volume reaction in the CVM extract (VeDDRA 2770). Plate stamps and neighbourhood peers follow.

#722 of 2,481
by report volume (all reactions)
404
reports citing this reaction
9.4%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Focal seizure has 404 reports now versus 391 in that prior snapshot: 13 more (3.3%).

Report change
+13
Death-coded reports
+0
Death-coded share
−0.3 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Focal seizure changes

FDA AER · VeDDRA plate

Code 2770 VOL-LOW

VOL-LOW · DEATH-PAR · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 404 reports
  • DEATH-PAR 9.4%
  • MID-PACK #722/2481
  • PHOTO-FINISH Swollen lymph node
  • SPECIES-DOG Dog · 363
  • DRUG-LEAD Pyrantel Pamoate;… · 108
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Swollen lymph node (±0 reports)

Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Focal seizure

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Loss of vision · near405Oral ulceration · near405Focal seizure · this reaction404Swollen lymph node · near404Drooping eyelid · near402Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Focal seizure

What the FDA AER plate says about Focal seizure

Signature read: 404 reports place Focal seizure in the upper third of FDA AER volume (#722 of 2,481). Report volume is upper-third scale: 404 named reports in the openFDA extract. 38 of 404 reports were death-coded (9.4% of named reports, not a population mortality rate). Nearest volume peer: Swollen lymph node (±0 reports). Lead species Dog (363). Lead co-reported drug Pyrantel Pamoate;Sarolaner (108).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Pyrantel Pamoate;Sarolaner appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 363
Cat 40
Horse 1

Breeds Most Affected

Retriever - Labrador 41
Retriever - Golden 34
Crossbred Canine/dog 32
Domestic Shorthair 26
Terrier - Yorkshire 17
Shepherd Dog - Australian 14
Boxer (German Boxer) 14
Terrier (unspecified) 11
Shepherd Dog - German 10
Chihuahua 8

Associated Drugs

Pyrantel Pamoate;Sarolaner 108
Bedinvetmab 47
Fluralaner 13.64% 12-Week Chew 44
Sarolaner 31
Afoxolaner 22
Carprofen 20
Moxidectin 20
Maropitant Citrate 19
Oclacitinib Maleate 18
Gabapentin 18
Lotilaner 14
Ivermectin + Pyrantel As Pamoate Salt 10
Fluralaner 5.46% 1-Month Chew 10
Frunevetmab 10
Fluralaner 9
Cefovecin 8
Milbemycin Oxime + Spinosad 7
Buprenorphine 7
Anti-Il31 Mab Mcs Lot #1283563 7
Milbemycin/Lufenuron Tablets 6

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Focal seizure, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (404 here).

Similar death-coded share

Nearest other reactions by death-coded share (9.4% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Focal seizure (#722 of 2,481 by report volume); death-coded 9.4%. PlainBreed reaction plate · report volume stamp 404 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →