Reaction profile

The FDA adverse-event record for synovial fluid, abnormal nos

33 FDA reports name synovial fluid, abnormal nos, a lower-volume reaction in the CVM extract (VeDDRA 2721). Plate stamps and neighbourhood peers follow.

#1948 of 2,481
by report volume (all reactions)
33
reports citing this reaction
9.1%
death-coded share
Horse
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Synovial fluid, abnormal NOS has 33 reports now versus 30 in that prior snapshot: 3 more (10.0%).

Report change
+3
Death-coded reports
+2
Death-coded share
+5.8 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Synovial fluid, abnormal NOS changes

FDA AER · VeDDRA plate

Code 2721 VOL-TRACE

VOL-TRACE · DEATH-PAR · LOWER-Q · PHOTO-FINISH · SPECIES-HORSE · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-TRACE 33 reports
  • DEATH-PAR 9.1%
  • LOWER-Q #1948/2481
  • PHOTO-FINISH Abnormal dexamethason…
  • SPECIES-HORSE Horse · 25
  • DRUG-LEAD Hyaluronate Sodium · 11
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Abnormal dexamethasone suppression test (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Lower-volume neighbourhood around Synovial fluid, abnormal NOS

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Abnormal dexamethason… · near33Burning mouth sensati… · near33Decreased number of s… · near33Displaced abomasum · near33Synovial fluid, abnor… · thi…33Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Synovial fluid, abnormal NOS

What the FDA AER plate says about Synovial fluid, abnormal NOS

Signature read: 3 death-coded reports is a thin tail count for Synovial fluid, abnormal NOS in the CVM extract. Report volume is lower-third scale: 33 named reports in the openFDA extract. 3 of 33 reports were death-coded (9.1% of named reports, not a population mortality rate). Nearest volume peer: Abnormal dexamethasone suppression test (±0 reports). Lead species Horse (25). Lead co-reported drug Hyaluronate Sodium (11).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Hyaluronate Sodium appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Horse 25
Dog 7
Cat 1

Breeds Most Affected

Quarter Horse 6
Horse (other) 3
Standardbred (unspecified) 2
Horse (unknown) 2
Thoroughbred 2
Standardbred - American 2
Mixed (Horse) 1
Domestic Shorthair 1
Retriever - Labrador 1
Appaloosa 1

Associated Drugs

Hyaluronate Sodium 11
Bedinvetmab 6
Triamcinolone Acetonide 5
Hyaluronic Acid 5
Polysulfated Glycosaminoglycan 3
Carprofen 3
Methylprednisolone Acetate 1
Methylprednisolone 1
Selamectin 1
Feline Calicivirus, Strain F-9, Passage 7, Lot A; Feline Panleukopenia Virus, St 1
Thiabendazole, Dexamethasone, Neomycin Sulfate 1
Ivermecin 1
Flea/Heartworm Preventative 1
Hyaluronate Sodium 10 Mg/Ml Solution For Injection 1
Dexmedetomidine Hydrochloride 1
Cytokines + Exosomes + Growth Factors 1
Thyrotabs 1
Gabapentin 1
Benadryl 1
Metronidazole 1

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Synovial fluid, abnormal NOS (#1948 of 2,481 by report volume); death-coded 9.1%. PlainBreed reaction plate · death-coded report count stamp 3 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →