Reaction profile

The FDA adverse-event record for lip paralysis

28 FDA reports name lip paralysis, a lower-volume reaction in the CVM extract (VeDDRA 1151). Plate stamps and neighbourhood peers follow.

#2029 of 2,481
by report volume (all reactions)
28
reports citing this reaction
7.1%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Lip paralysis has 28 reports now versus 28 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Lip paralysis changes

FDA AER · VeDDRA plate

Code 1151 VOL-TRACE

VOL-TRACE · DEATH-PAR · LOWER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-TRACE 28 reports
  • DEATH-PAR 7.1%
  • LOWER-Q #2029/2481
  • PHOTO-FINISH Absence seizure
  • SPECIES-DOG Dog · 20
  • DRUG-LEAD Milbemycin Oxime… · 5
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Absence seizure (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Lower-volume neighbourhood around Lip paralysis

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Absence seizure · near28Application site brui… · near28BILIRUBIN(DIRECT) HIG… · near28Cholangitis · near28Lip paralysis · this reaction28Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Lip paralysis

Lip paralysis: low death-coded share in the FDA AER plate

Signature read: 2 death-coded reports is a thin tail count for Lip paralysis in the CVM extract. Report volume is lower-third scale: 28 named reports in the openFDA extract. Death-coded share is lower-third: 2 of 28 reports (7.1% of named reports). Nearest volume peer: Absence seizure (±0 reports). Lead species Dog (20). Lead co-reported drug Milbemycin Oxime + Spinosad (5).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Milbemycin Oxime + Spinosad appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 20
Horse 7
Mule 1

Breeds Most Affected

Boxer (German Boxer) 3
Pit Bull 3
Quarter Horse 2
Bulldog - French 2
Rottweiler 1
Retriever - Labrador 1
Shiba Inu 1
Retriever - Golden 1
Shepherd Dog - German 1
Warmblood (unspecified) 1

Associated Drugs

Milbemycin Oxime + Spinosad 5
Ivermectin(1.55%)/Praziquantel(7.75%) Paste 4
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 4
Oclacitinib Maleate 2
Prednisone 2
Enrofloxacin 2
Maropitant Citrate 2
Diphenhydramine 2
Florfenicol + Mometasone Furoate + Terbinafine 2
Insulin (Unknown) 1
Melarsomine Dihydrochloride Injection 1
Firocoxib 227 Mg Chewable 1
Trilostane 1
Compounded Trilostane 1
Pimobendan 1
Meclizine 1
Ivermectin 1.87% Paste 1
Afoxolaner 1
Ivermectin + Pyrantel As Pamoate Salt 1
Levothyroxine Sodium 1

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Lip paralysis (#2029 of 2,481 by report volume); death-coded 7.1%. PlainBreed reaction plate · death-coded report count stamp 2 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →