Swallowing difficult

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VeDDRA Code: 1808

289 adverse event reports referencing this reaction

289
Total Reports
61
Deaths
2110.0%
Death Rate

Species Most Affected

Dog 211
Cat 61
Horse 12
Human 3
Cattle 1
Donkey 1

Breeds Most Affected

Domestic Shorthair 37
Retriever - Labrador 21
Crossbred Canine/dog 20
Retriever - Golden 14
Chihuahua 13
Pit Bull 9
Cat (unknown) 9
Boxer (German Boxer) 8
Dog (unknown) 7
Shepherd Dog - German 7

Associated Drugs

Maropitant Citrate 36
Milbemycin Oxime + Spinosad 23
Afoxolaner 23
Carprofen 19
Trilostane 16
Oclacitinib Maleate 15
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 13
Buprenorphine 12
Metronidazole 11
Fluralaner Chew Tablets 11
Pyrantel Pamoate;Sarolaner 11
Bedinvetmab 11
Selamectin 10
Ivermectin + Pyrantel As Pamoate Salt 10
Spinosad 9
Enrofloxacin 9
Moxidectin 8
Sarolaner 8
Anti-Il31 Mab Mcs Lot #1283563 8
Gabapentin 8

Data Summary

Metric Value
Total reports referencing reaction 289
Reports with fatal outcome 61
Case-fatality rate (reported events) 2110.0%
Species observed 6
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 1808.

Swallowing difficult Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 289 adverse event reports that reference Swallowing difficult as a reaction term, including 61 reports with a death outcome — a 2110.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 1808, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Swallowing difficult appears most frequently in reports for Dog (211 reports), Cat (61 reports), Horse (12 reports) — with Dog dominating at 211 entries. Within those species, the breeds most often named alongside this reaction are Domestic Shorthair (37), Retriever - Labrador (21), Crossbred Canine/dog (20). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Swallowing difficult are Maropitant Citrate (36 reports), Milbemycin Oxime + Spinosad (23 reports), Afoxolaner (23 reports), Carprofen (19 reports), with Maropitant Citrate appearing alongside this reaction in 36 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial