Low parathyroid (PTH) concentration

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VeDDRA Code: 2665

10 adverse event reports referencing this reaction

10
Total Reports
1
Deaths
1000.0%
Death Rate

Species Most Affected

Cat 7
Dog 3

Breeds Most Affected

Domestic Shorthair 4
Retriever - Golden 1
Retriever - Flat-coated 1
Shih Tzu 1
American Curl Shorthair 1
American Shorthair 1
Cat (unknown) 1

Associated Drugs

Bexagliflozin 3
Velagliflozin Proline Monohydrate 2
Ente Ointment 2
Doxycycline 2
Robenacoxib 1
Buprenorphine 1
Fluid Therapy (Unknown) 1
Afoxolaner 1
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 1
Melarsomine Dihydrochloride 1
Frunevetmab 1
Senvelgo Velagliflozin Oral Solution 1

Data Summary

Metric Value
Total reports referencing reaction 10
Reports with fatal outcome 1
Case-fatality rate (reported events) 1000.0%
Species observed 2
Breeds observed 7
Drugs associated with reaction 12

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 2665.

Low parathyroid (PTH) concentration Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 10 adverse event reports that reference Low parathyroid (PTH) concentration as a reaction term, including 1 reports with a death outcome — a 1000.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 2665, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Low parathyroid (PTH) concentration appears most frequently in reports for Cat (7 reports), Dog (3 reports) — with Cat dominating at 7 entries. Within those species, the breeds most often named alongside this reaction are Domestic Shorthair (4), Retriever - Golden (1), Retriever - Flat-coated (1). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Low parathyroid (PTH) concentration are Bexagliflozin (3 reports), Velagliflozin Proline Monohydrate (2 reports), Ente Ointment (2 reports), Doxycycline (2 reports), with Bexagliflozin appearing alongside this reaction in 3 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial