SKIN SCRAPING ABNORMAL

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VeDDRA Code: 99353

158 adverse event reports referencing this reaction

158
Total Reports
3
Deaths
190.0%
Death Rate

Species Most Affected

Dog 110
Cattle 47
Cat 1

Breeds Most Affected

Aberdeen Angus 19
Shih Tzu 12
Retriever - Labrador 11
Crossbred Bovine/Cattle 11
Cattle (unknown) 8
Dog (unknown) 7
Holstein-Friesian also known as Holstein 4
Terrier (unspecified) 4
Bulldog 4
Shepherd Dog - German 4

Associated Drugs

Oclacitinib Maleate 76
Portech App Gun 65 Ml Ivomec/Eprinex 32
Ivermectin 0.5% Pour-On Topical Solution 26
Milbemycin Oxime + Spinosad 14
Eprinomectin 5 Mg/Ml Pour-On Solution 13
Selamectin 10
Cefpodoxime Proxetil 9
Ivermectin 6
Prednisolone; Trimeprazine Tartrate 5
Fluralaner Chew Tablets 5
Prednisone 4
Cetirizine Hcl 4
Cyclosporine 3
Moxidectin 3
Maropitant Citrate 3
Allergy 3
Ivermectin(1%)/Clorsulon(10%) Injection 3
Loratidine 3
Cefovecin 3
Amoxicillin (As Trihydrate); Clavulanate Potassium ( K-Clavulanate) 3

Data Summary

Metric Value
Total reports referencing reaction 158
Reports with fatal outcome 3
Case-fatality rate (reported events) 190.0%
Species observed 3
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 99353.

SKIN SCRAPING ABNORMAL Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 158 adverse event reports that reference SKIN SCRAPING ABNORMAL as a reaction term, including 3 reports with a death outcome — a 190.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 99353, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

SKIN SCRAPING ABNORMAL appears most frequently in reports for Dog (110 reports), Cattle (47 reports), Cat (1 reports) — with Dog dominating at 110 entries. Within those species, the breeds most often named alongside this reaction are Aberdeen Angus (19), Shih Tzu (12), Retriever - Labrador (11). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with SKIN SCRAPING ABNORMAL are Oclacitinib Maleate (76 reports), Portech App Gun 65 Ml Ivomec/Eprinex (32 reports), Ivermectin 0.5% Pour-On Topical Solution (26 reports), Milbemycin Oxime + Spinosad (14 reports), with Oclacitinib Maleate appearing alongside this reaction in 76 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial