Fluid in abdomen NOS

Verify with FDA CVM →

VeDDRA Code: 2011

696 adverse event reports referencing this reaction

696
Total Reports
372
Deaths
5340.0%
Death Rate

Species Most Affected

Dog 594
Cat 87
Cattle 9
Horse 2
Pig 2
Sheep 1
Ferret 1

Breeds Most Affected

Retriever - Labrador 119
Domestic Shorthair 52
Retriever - Golden 37
Shepherd Dog - German 27
Crossbred Canine/dog 26
Boxer (German Boxer) 25
Rottweiler 25
Chihuahua 17
Beagle 15
Shepherd Dog - Australian 15

Associated Drugs

Carprofen 128
Deracoxib 93
Maropitant Citrate 88
Gabapentin 59
Milbemycin Oxime + Spinosad 49
Tramadol 46
Oclacitinib Maleate 46
Enrofloxacin 45
Isoflurane 41
Famotidine 38
Bedinvetmab 37
Meloxicam 32
Buprenorphine 32
Metronidazole 31
Cefovecin 28
Propofol 26
Moxidectin 25
Grapiprant 25
Afoxolaner 24
Spinosad 23

Data Summary

Metric Value
Total reports referencing reaction 696
Reports with fatal outcome 372
Case-fatality rate (reported events) 5340.0%
Species observed 7
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 2011.

Fluid in abdomen NOS Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 696 adverse event reports that reference Fluid in abdomen NOS as a reaction term, including 372 reports with a death outcome — a 5340.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 2011, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Fluid in abdomen NOS appears most frequently in reports for Dog (594 reports), Cat (87 reports), Cattle (9 reports) — with Dog dominating at 594 entries. Within those species, the breeds most often named alongside this reaction are Retriever - Labrador (119), Domestic Shorthair (52), Retriever - Golden (37). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Fluid in abdomen NOS are Carprofen (128 reports), Deracoxib (93 reports), Maropitant Citrate (88 reports), Gabapentin (59 reports), with Carprofen appearing alongside this reaction in 128 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial