Reaction profile

The FDA adverse-event record for nervous

88 FDA adverse-event reports reference nervous (VeDDRA 3063). See the species, breeds, and drugs most associated with it below.

88
reports citing this reaction
4.5%
death-coded share
Dog
most-affected species
Bedinvetmab
most-associated drug
Verify with FDA CVM →
88
Total Reports
4
Deaths
4.5%
Death Rate

Species Most Affected

Dog 67
Cat 16
Human 3
Horse 2

Breeds Most Affected

Domestic Shorthair 13
Retriever - Labrador 13
Chihuahua 6
Shih Tzu 3
Unknown 3
Shepherd Dog - German 3
Retriever - Golden 3
Crossbred Canine/dog 3
Siberian Husky 2
Pit Bull 2

Associated Drugs

Bedinvetmab 15
Pyrantel Pamoate;Sarolaner 7
Gabapentin 7
Maropitant Citrate 7
Trilostane 5
Milbemycin Oxime + Praziquantel 5
Carprofen 5
Eprinomectin + Esafoxolaner + Praziquantel 4
Fluralaner 13.64% 12-Week Chew 4
Afoxolaner 4
Oclacitinib Maleate 3
Bexagliflozin 3
Nitenpyram 3
Fluid Therapy 3
Incurin 3
Denamarin 3
Unknown Joint Supplement 3
Diphenhydramine 3
Buprenorphine 2
Imidacloprid 2

Nervous Reaction Insights

88 reports name Nervous; 4 recorded a death outcome (4.5% of reported events, not a population-level mortality rate). VeDDRA code: 3063.

By species: Dog (67 reports), Cat (16 reports), Human (3 reports). By breed: Domestic Shorthair (13), Retriever - Labrador (13), Chihuahua (6).

Most co-reported drugs: Bedinvetmab (15 reports), Pyrantel Pamoate;Sarolaner (7 reports), Gabapentin (7 reports), Maropitant Citrate (7 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.