Reaction profile

The FDA adverse-event record for nervous

117 FDA adverse-event reports reference nervous (VeDDRA 3063). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1316 of 2,481
by report volume (all reactions)
117
reports citing this reaction
4.3%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Nervous has 117 reports now versus 106 in that prior snapshot: 11 more (10.4%).

Report change
+11
Death-coded reports
+0
Death-coded share
−0.4 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Nervous changes

FDA AER · VeDDRA plate

Code 3063 VOL-LOW

VOL-LOW · DEATH-LOW · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 117 reports
  • DEATH-LOW 4.3%
  • MID-PACK #1316/2481
  • PHOTO-FINISH Cold feeling of extre…
  • SPECIES-DOG Dog · 87
  • DRUG-LEAD Bedinvetmab · 17
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Cold feeling of extremity (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Nervous

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Cold feeling of extre… · near117Mental function decre… · near117Nervous · this reaction117Rotatory nystagmus · near117Teeth grinding · near117Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Nervous

Nervous: low death-coded share in the FDA AER plate

Signature read: Nervous's 4.3% death-coded share is among the lowest in the openFDA reaction corpus. Report volume sits in the middle third of the reaction corpus. Death-coded share is lower-third: 5 of 117 reports (4.3% of named reports). Nearest volume peer: Cold feeling of extremity (±0 reports). Lead species Dog (87). Lead co-reported drug Bedinvetmab (17).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Bedinvetmab appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 87
Cat 24
Human 4
Horse 2

Breeds Most Affected

Domestic Shorthair 20
Retriever - Labrador 13
Chihuahua 8
Crossbred Canine/dog 6
Shih Tzu 4
Unknown 4
Pit Bull 4
Siberian Husky 3
Shepherd Dog - German 3
Retriever - Golden 3

Associated Drugs

Bedinvetmab 17
Pyrantel Pamoate;Sarolaner 10
Gabapentin 8
Milbemycin Oxime + Praziquantel 8
Maropitant Citrate 8
Trilostane 7
Buprenorphine 6
Carprofen 6
Eprinomectin + Esafoxolaner + Praziquantel 5
Nitenpyram 5
Lotilaner 5
Bexagliflozin 4
Fluralaner 13.64% 12-Week Chew 4
Afoxolaner 4
Fluid Therapy 4
Oclacitinib Maleate 3
Ilunocitinib 3
Imidacloprid 3
Incurin 3
Denamarin 3

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Nervous, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (117 here).

Similar death-coded share

Nearest other reactions by death-coded share (4.3% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Nervous (#1316 of 2,481 by report volume); death-coded 4.3%. PlainBreed reaction plate · death-coded share stamp 4.3% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →