Reaction profile

The FDA adverse-event record for decreased haemoglobin

1,007 FDA reports name decreased haemoglobin, a high-volume reaction in the CVM extract (VeDDRA 2214). Plate stamps and neighbourhood peers follow.

#391 of 2,481
by report volume (all reactions)
1,007
reports citing this reaction
26.9%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Decreased haemoglobin has 1,007 reports now versus 957 in that prior snapshot: 50 more (5.2%).

Report change
+50
Death-coded reports
+8
Death-coded share
−0.6 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Decreased haemoglobin changes

FDA AER · VeDDRA plate

Code 2214 VOL-MID

VOL-MID · DEATH-HOT · UPPER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-MID 1,007 reports
  • DEATH-HOT 26.9%
  • UPPER-Q #391/2481
  • PHOTO-FINISH Itchy skin
  • SPECIES-DOG Dog · 851
  • DRUG-LEAD Carprofen · 101
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Itchy skin (±2 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Decreased haemoglobin

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Paddling · near1009Pulmonary oedema · near1009Decreased haemoglobin · this…1007Itchy skin · near1005Lack of efficacy (hea… · near1001Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Decreased haemoglobin

Decreased haemoglobin: high death-coded share in the FDA AER plate

Signature read: 271 death-coded reports is a heavy tail count for Decreased haemoglobin in the CVM extract. Report volume is upper-third scale: 1,007 named reports in the openFDA extract. Death-coded share is upper-third: 271 of 1,007 reports (26.9% of named reports). Nearest volume peer: Itchy skin (±2 reports). Lead species Dog (851). Lead co-reported drug Carprofen (101).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 851
Cat 147
Horse 7
Sheep 1
Cattle 1

Breeds Most Affected

Retriever - Labrador 107
Domestic Shorthair 104
Crossbred Canine/dog 77
Retriever - Golden 56
Shepherd Dog - German 26
Chihuahua 25
Pit Bull 20
Shih Tzu 18
Terrier (unspecified) 18
Terrier - Yorkshire 16

Associated Drugs

Carprofen 101
Oclacitinib Maleate 87
Maropitant Citrate 83
Ilunocitinib 76
Prednisone 70
Fluralaner Chew Tablets 70
Afoxolaner 59
Trilostane 55
Gabapentin 46
Fluralaner 13.64% 12-Week Chew 46
Enrofloxacin 44
Doxycycline 43
Metronidazole 40
Ivermectin + Pyrantel As Pamoate Salt 35
Lotilaner 34
Buprenorphine 33
Milbemycin Oxime + Praziquantel 32
Famotidine 30
Rabies Vaccine 30
Diphenhydramine 28

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Decreased haemoglobin, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (1,007 here).

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Decreased haemoglobin (#391 of 2,481 by report volume); death-coded 26.9%. PlainBreed reaction plate · death-coded report count stamp 271 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →