Reaction profile

The FDA adverse-event record for decreased haemoglobin

881 FDA adverse-event reports reference decreased haemoglobin (VeDDRA 2214). See the species, breeds, and drugs most associated with it below.

881
reports citing this reaction
27.4%
death-coded share
Dog
most-affected species
Carprofen
most-associated drug
Verify with FDA CVM →
881
Total Reports
241
Deaths
27.4%
Death Rate

Species Most Affected

Dog 746
Cat 129
Horse 5
Sheep 1

Breeds Most Affected

Domestic Shorthair 89
Retriever - Labrador 86
Crossbred Canine/dog 66
Retriever - Golden 51
Chihuahua 24
Shepherd Dog - German 23
Shih Tzu 18
Terrier (unspecified) 16
Pit Bull 15
Dog (unknown) 15

Associated Drugs

Carprofen 94
Oclacitinib Maleate 71
Fluralaner Chew Tablets 70
Maropitant Citrate 67
Prednisone 60
Afoxolaner 57
Trilostane 53
Enrofloxacin 41
Fluralaner 13.64% 12-Week Chew 37
Doxycycline 36
Gabapentin 36
Ivermectin + Pyrantel As Pamoate Salt 34
Metronidazole 34
Ilunocitinib 33
Buprenorphine 29
Milbemycin Oxime + Praziquantel 28
Meloxicam 27
Famotidine 26
Bedinvetmab 26
Grapiprant 24

Decreased haemoglobin Reaction Insights

881 reports name Decreased haemoglobin; 241 recorded a death outcome (27.4% of reported events, not a population-level mortality rate). VeDDRA code: 2214.

By species: Dog (746 reports), Cat (129 reports), Horse (5 reports). By breed: Domestic Shorthair (89), Retriever - Labrador (86), Crossbred Canine/dog (66).

Most co-reported drugs: Carprofen (94 reports), Oclacitinib Maleate (71 reports), Fluralaner Chew Tablets (70 reports), Maropitant Citrate (67 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.