Reaction profile

The FDA adverse-event record for lymphadenopathy

883 FDA adverse-event reports reference lymphadenopathy (VeDDRA 174). See the species, breeds, and drugs most associated with it below.

883
reports citing this reaction
27.3%
death-coded share
Dog
most-affected species
Oclacitinib Maleate
most-associated drug
Verify with FDA CVM →
883
Total Reports
241
Deaths
27.3%
Death Rate

Species Most Affected

Dog 752
Cat 115
Cattle 9
Horse 4
Human 1
Pig 1
Ferret 1

Breeds Most Affected

Retriever - Labrador 90
Domestic Shorthair 49
Crossbred Canine/dog 42
Retriever - Golden 39
Shepherd Dog - German 39
Boxer (German Boxer) 31
Domestic (unspecified) 28
Shih Tzu 27
Terrier - Bull - American Pit 24
Rottweiler 16

Associated Drugs

Oclacitinib Maleate 169
Carprofen 96
Maropitant Citrate 72
Milbemycin Oxime + Spinosad 68
Cyclosporine A 57
Cyclosporine 54
Prednisone 43
Afoxolaner 40
Moxidectin 39
Deracoxib 39
Gabapentin 37
Enrofloxacin 36
Bedinvetmab 34
Doxycycline 27
Famotidine 26
Cephalexin 26
Spinosad 25
Robenacoxib 25
Meloxicam 23
Buprenorphine 23

Lymphadenopathy Reaction Insights

883 reports name Lymphadenopathy; 241 recorded a death outcome (27.3% of reported events, not a population-level mortality rate). VeDDRA code: 174.

By species: Dog (752 reports), Cat (115 reports), Cattle (9 reports). By breed: Retriever - Labrador (90), Domestic Shorthair (49), Crossbred Canine/dog (42).

Most co-reported drugs: Oclacitinib Maleate (169 reports), Carprofen (96 reports), Maropitant Citrate (72 reports), Milbemycin Oxime + Spinosad (68 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.