Reaction profile

The FDA adverse-event record for magnesium high, blood

71 FDA adverse-event reports reference magnesium high, blood (VeDDRA 99282). See the species, breeds, and drugs most associated with it below.

71
reports citing this reaction
43.7%
death-coded share
Dog
most-affected species
Meloxicam
most-associated drug
Verify with FDA CVM →
71
Total Reports
31
Deaths
43.7%
Death Rate

Species Most Affected

Dog 47
Cat 23
Cattle 1

Breeds Most Affected

Domestic Shorthair 11
Domestic (unspecified) 9
Retriever - Labrador 7
Crossbred Canine/dog 4
Retriever - Golden 4
Shih Tzu 3
Pinscher - Miniature 3
Poodle (unspecified) 2
Mixed (Dog) 2
Poodle - Toy 2

Associated Drugs

Meloxicam 11
Milbemycin Oxime + Spinosad 7
Spinosad 6
Trilostane 5
Afoxolaner 5
Polysulfated Glycosaminoglycan 4
Ivermectin + Pyrantel As Pamoate Salt 4
Maropitant Citrate 3
Cefovecin 3
Tramadol 3
Cefovecin Sodium 2
Rabies Vaccine 2
Famotidine 2
Milk Thistle 2
Emodepside + Praziquantel 2
Firocoxib 2
Nitenpyram 2
Insulin 2
Diphenhydramine 2
Deracoxib 2

MAGNESIUM HIGH, BLOOD Reaction Insights

71 reports name MAGNESIUM HIGH, BLOOD; 31 recorded a death outcome (43.7% of reported events, not a population-level mortality rate). VeDDRA code: 99282.

By species: Dog (47 reports), Cat (23 reports), Cattle (1 reports). By breed: Domestic Shorthair (11), Domestic (unspecified) (9), Retriever - Labrador (7).

Most co-reported drugs: Meloxicam (11 reports), Milbemycin Oxime + Spinosad (7 reports), Spinosad (6 reports), Trilostane (5 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.