Reaction profile

The FDA adverse-event record for culture/titer data abnormal

1,056 FDA adverse-event reports reference culture/titer data abnormal (VeDDRA 99241). See the species, breeds, and drugs most associated with it below.

1,056
reports citing this reaction
41.7%
death-coded share
Dog
most-affected species
Ceftiofur Crystalline Free Acid
most-associated drug
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1,056
Total Reports
440
Deaths
41.7%
Death Rate

Species Most Affected

Dog 589
Cattle 355
Cat 69
Horse 32
Pig 7
Sheep 2
Fish 1
Turkey 1

Breeds Most Affected

Holstein-Friesian also known as Holstein 102
Retriever - Labrador 99
Cattle (other) 93
Crossbred Bovine/Cattle 64
Crossbred Canine/dog 44
Mixed (Cattle) 39
Cattle (unknown) 32
Retriever - Golden 29
Shepherd Dog - German 24
Domestic Shorthair 23

Associated Drugs

Ceftiofur Crystalline Free Acid 91
Betamethasone + Florfenicol + Terbinafine 82
Tulathromycin 73
Tildipirosin 63
Lotilaner 62
Carprofen 61
Trilostane 55
Oclacitinib Maleate 45
Bovine Parainfluenza Virus 3 (Ts), Rlb103 (Nl-Bk-6), Mlv; Bovine Respiratory Syn 40
Fluralaner Chew Tablets 40
Florfenicol, Flunixin 39
Cefovecin 39
Bovine Respiratory Syncytial Virus, 597-10 10Th Psg Strain 375; Bovine Viral Dia 35
Pyrantel Pamoate;Sarolaner 35
Afoxolaner 31
Prednisone 29
Maropitant Citrate 29
Moxidectin 28
Bovine Parainfluenza Virus 3, Reisinger(Nl-Bk-6), Mlv; Bovine Respiratory Syncyt 25
Cyclosporine 23

CULTURE/TITER DATA ABNORMAL Reaction Insights

1,056 reports name CULTURE/TITER DATA ABNORMAL; 440 recorded a death outcome (41.7% of reported events, not a population-level mortality rate). VeDDRA code: 99241.

By species: Dog (589 reports), Cattle (355 reports), Cat (69 reports). By breed: Holstein-Friesian also known as Holstein (102), Retriever - Labrador (99), Cattle (other) (93).

Most co-reported drugs: Ceftiofur Crystalline Free Acid (91 reports), Betamethasone + Florfenicol + Terbinafine (82 reports), Tulathromycin (73 reports), Tildipirosin (63 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.