CULTURE/TITER DATA ABNORMAL

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VeDDRA Code: 99241

1,056 adverse event reports referencing this reaction

1,056
Total Reports
440
Deaths
4170.0%
Death Rate

Species Most Affected

Dog 589
Cattle 355
Cat 69
Horse 32
Pig 7
Sheep 2
Fish 1
Turkey 1

Breeds Most Affected

Holstein-Friesian also known as Holstein 102
Retriever - Labrador 99
Cattle (other) 93
Crossbred Bovine/Cattle 64
Crossbred Canine/dog 44
Mixed (Cattle) 39
Cattle (unknown) 32
Retriever - Golden 29
Shepherd Dog - German 24
Domestic Shorthair 23

Associated Drugs

Ceftiofur Crystalline Free Acid 91
Betamethasone + Florfenicol + Terbinafine 82
Tulathromycin 73
Tildipirosin 63
Lotilaner 62
Carprofen 61
Trilostane 55
Oclacitinib Maleate 45
Bovine Parainfluenza Virus 3 (Ts), Rlb103 (Nl-Bk-6), Mlv; Bovine Respiratory Syn 40
Fluralaner Chew Tablets 40
Florfenicol, Flunixin 39
Cefovecin 39
Bovine Respiratory Syncytial Virus, 597-10 10Th Psg Strain 375; Bovine Viral Dia 35
Pyrantel Pamoate;Sarolaner 35
Afoxolaner 31
Prednisone 29
Maropitant Citrate 29
Moxidectin 28
Bovine Parainfluenza Virus 3, Reisinger(Nl-Bk-6), Mlv; Bovine Respiratory Syncyt 25
Cyclosporine 23

Data Summary

Metric Value
Total reports referencing reaction 1,056
Reports with fatal outcome 440
Case-fatality rate (reported events) 4170.0%
Species observed 8
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 99241.

CULTURE/TITER DATA ABNORMAL Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 1,056 adverse event reports that reference CULTURE/TITER DATA ABNORMAL as a reaction term, including 440 reports with a death outcome — a 4170.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 99241, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

CULTURE/TITER DATA ABNORMAL appears most frequently in reports for Dog (589 reports), Cattle (355 reports), Cat (69 reports) — with Dog dominating at 589 entries. Within those species, the breeds most often named alongside this reaction are Holstein-Friesian also known as Holstein (102), Retriever - Labrador (99), Cattle (other) (93). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with CULTURE/TITER DATA ABNORMAL are Ceftiofur Crystalline Free Acid (91 reports), Betamethasone + Florfenicol + Terbinafine (82 reports), Tulathromycin (73 reports), Tildipirosin (63 reports), with Ceftiofur Crystalline Free Acid appearing alongside this reaction in 91 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial