Reaction profile

The FDA adverse-event record for culture/titer data abnormal

1,061 FDA reports name culture/titer data abnormal, a high-volume reaction in the CVM extract (VeDDRA 99241). Plate stamps and neighbourhood peers follow.

#375 of 2,481
by report volume (all reactions)
1,061
reports citing this reaction
41.6%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. CULTURE/TITER DATA ABNORMAL has 1,061 reports now versus 1,057 in that prior snapshot: 4 more (0.4%).

Report change
+4
Death-coded reports
+1
Death-coded share
−0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to CULTURE/TITER DATA ABNORMAL changes

FDA AER · VeDDRA plate

Code 99241 VOL-MID

VOL-MID · DEATH-HOT · UPPER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-MID 1,061 reports
  • DEATH-HOT 41.6%
  • UPPER-Q #375/2481
  • PHOTO-FINISH INEFFECTIVE, ANTIINFL…
  • SPECIES-DOG Dog · 591
  • DRUG-LEAD Ceftiofur Crystal… · 92
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: INEFFECTIVE, ANTIINFLAMMATORY (±2 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around CULTURE/TITER DATA ABNORMAL

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348CULTURE/TITER DATA AB… · thi…1061INEFFECTIVE, ANTIINFL… · near1059Corneal ulcer · near1054Elevated creatine-kin… · near1053Discoloured urine · near1051Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around CULTURE/TITER DATA ABNORMAL

CULTURE/TITER DATA ABNORMAL: high death-coded share in the FDA AER plate

Signature read: 441 death-coded reports is a heavy tail count for CULTURE/TITER DATA ABNORMAL in the CVM extract. Report volume is upper-third scale: 1,061 named reports in the openFDA extract. Death-coded share is upper-third: 441 of 1,061 reports (41.6% of named reports). Nearest volume peer: INEFFECTIVE, ANTIINFLAMMATORY (±2 reports). Lead species Dog (591). Lead co-reported drug Ceftiofur Crystalline Free Acid (92).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 591
Cattle 355
Cat 69
Horse 35
Pig 7
Sheep 2
Fish 1
Turkey 1

Breeds Most Affected

Holstein-Friesian also known as Holstein 102
Retriever - Labrador 99
Cattle (other) 93
Crossbred Bovine/Cattle 64
Crossbred Canine/dog 44
Mixed (Cattle) 39
Cattle (unknown) 32
Retriever - Golden 29
Shepherd Dog - German 24
Domestic Shorthair 23

Associated Drugs

Ceftiofur Crystalline Free Acid 92
Betamethasone + Florfenicol + Terbinafine 82
Tulathromycin 73
Tildipirosin 63
Carprofen 62
Lotilaner 62
Trilostane 55
Oclacitinib Maleate 46
Bovine Parainfluenza Virus 3 (Ts), Rlb103 (Nl-Bk-6), Mlv; Bovine Respiratory Syn 40
Fluralaner Chew Tablets 40
Florfenicol, Flunixin 39
Cefovecin 39
Bovine Respiratory Syncytial Virus, 597-10 10Th Psg Strain 375; Bovine Viral Dia 35
Pyrantel Pamoate;Sarolaner 35
Afoxolaner 31
Prednisone 29
Maropitant Citrate 29
Moxidectin 28
Bovine Parainfluenza Virus 3, Reisinger(Nl-Bk-6), Mlv; Bovine Respiratory Syncyt 25
Cyclosporine 23

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for CULTURE/TITER DATA ABNORMAL, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar death-coded share

Nearest other reactions by death-coded share (41.6% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for CULTURE/TITER DATA ABNORMAL (#375 of 2,481 by report volume); death-coded 41.6%. PlainBreed reaction plate · death-coded report count stamp 441 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →