Reaction profile

The FDA adverse-event record for hot spot (pyotraumatic dermatitis)

1,604 FDA reports name hot spot (pyotraumatic dermatitis), a high-volume reaction in the CVM extract (VeDDRA 1200). Plate stamps and neighbourhood peers follow.

#273 of 2,481
by report volume (all reactions)
1,604
reports citing this reaction
2.7%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Hot spot (pyotraumatic dermatitis) has 1,604 reports now versus 1,591 in that prior snapshot: 13 more (0.8%).

Report change
+13
Death-coded reports
+1
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Hot spot (pyotraumatic dermatitis) changes

FDA AER · VeDDRA plate

Code 1200 VOL-MID

VOL-MID · DEATH-LOW · UPPER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-MID 1,604 reports
  • DEATH-LOW 2.7%
  • UPPER-Q #273/2481
  • PHOTO-FINISH Skin sore
  • SPECIES-DOG Dog · 1,483
  • DRUG-LEAD Milbemycin Oxime… · 318
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Skin sore (±2 reports)

Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Hot spot

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Crust · near1615Unsteady gait · near1607Skin sore · near1606Hot spot (pyotraumati… · thi…1604Hyperproteinaemia · near1597Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Hot spot (pyotraumatic dermatitis)

Hot spot (pyotraumatic dermatitis): low death-coded share in the FDA AER plate

Signature read: 1,604 reports place Hot spot (pyotraumatic dermatitis) in the upper third of FDA AER volume (#273 of 2,481). Report volume is upper-third scale: 1,604 named reports in the openFDA extract. Death-coded share is lower-third: 43 of 1,604 reports (2.7% of named reports). Nearest volume peer: Skin sore (±2 reports). Lead species Dog (1,483). Lead co-reported drug Milbemycin Oxime + Spinosad (318).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Milbemycin Oxime + Spinosad appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 1,483
Cat 121

Breeds Most Affected

Retriever - Labrador 198
Retriever - Golden 155
Shepherd Dog - German 90
Domestic Shorthair 85
Crossbred Canine/dog 81
Dog (unknown) 59
Shepherd Dog - Australian 50
Shih Tzu 42
Chihuahua 40
Bichon Frise 39

Associated Drugs

Milbemycin Oxime + Spinosad 318
Afoxolaner 183
Oclacitinib Maleate 102
Carprofen 97
Bedinvetmab 95
Fluralaner Chew Tablets 94
Spinosad 87
Ivermectin + Pyrantel As Pamoate Salt 69
Frunevetmab 63
Fluralaner 13.64% 12-Week Chew 54
Imidacloprid + Moxidectin 49
Trilostane 44
Selamectin 44
Milbemycin Oxime + Praziquantel 43
Prednisone 43
Pyrantel Pamoate;Sarolaner 42
Gabapentin 38
Sarolaner 35
Moxidectin 34
Maropitant Citrate 27

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Hot spot (pyotraumatic dermatitis), both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (1,604 here).

Similar death-coded share

Nearest other reactions by death-coded share (2.7% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Hot spot (pyotraumatic dermatitis) (#273 of 2,481 by report volume); death-coded 2.7%. PlainBreed reaction plate · report volume stamp 1,604 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →