Reaction profile

The FDA adverse-event record for adaptor, breakage

192 FDA adverse-event reports reference adaptor, breakage (VeDDRA 93135). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1058 of 2,481
by report volume (all reactions)
192
reports citing this reaction
0.0%
death-coded share
Unknown
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Adaptor, breakage has 192 reports now versus 190 in that prior snapshot: 2 more (1.1%).

Report change
+2
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Adaptor, breakage changes

FDA AER · VeDDRA plate

Code 93135 VOL-LOW

VOL-LOW · DEATH-RARE · MID-PACK · PHOTO-FINISH · SPECIES-UNKNOWN · DRUG-LEAD · DESK-NARROW · BOOK-FULL

  • VOL-LOW 192 reports
  • DEATH-RARE 0.0%
  • MID-PACK #1058/2481
  • PHOTO-FINISH Joint pain NOS
  • SPECIES-UNKNOWN Unknown · 191
  • DRUG-LEAD Cyclosporine · 183
  • DESK-NARROW 2 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Joint pain NOS (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Adaptor, breakage

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Cardiac murmur · near193Adaptor, breakage · this rea…192Joint pain NOS · near192Other immune system d… · near192Bloody stool · near191Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Adaptor, breakage

Adaptor, breakage: low death-coded share in the FDA AER plate

Signature read: Adaptor, breakage's 0.0% death-coded share is among the lowest in the openFDA reaction corpus. Report volume sits in the middle third of the reaction corpus. Death-coded share is lower-third: 0 of 192 reports (0.0% of named reports). Nearest volume peer: Joint pain NOS (±0 reports). Lead species Unknown (191). Lead co-reported drug Cyclosporine (183).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Cyclosporine appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Unknown 191
Cat 1

Breeds Most Affected

Unknown 191
Cat (unknown) 1

Associated Drugs

Cyclosporine 183
Molidustat 6
Meloxicam 1
Amoxicillin Trihydrate, Clavulanate Potassium 1
Pregabalin 1
Metronidazole 1
Molidustat Sodium 1

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Adaptor, breakage, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (192 here).

Similar death-coded share

Nearest other reactions by death-coded share (0.0% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Adaptor, breakage (#1058 of 2,481 by report volume); death-coded 0.0%. PlainBreed reaction plate · death-coded share stamp 0.0% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →