Lack of efficacy (ectoparasite) - flea
VeDDRA Code: 2649
56,197 adverse event reports referencing this reaction
56,197
Total Reports
171
Deaths
30.0%
Death Rate
Species Most Affected
Dog 46,281
Cat 9,846
Other 33
Unknown 16
Rabbit 8
Ferret 4
Other Canids 2
Fox 2
Cattle 1
Macaw 1
Breeds Most Affected
Dog (unknown) 5,693
Crossbred Canine/dog 4,738
Domestic Shorthair 4,360
Chihuahua 3,703
Retriever - Labrador 2,361
Terrier - Yorkshire 2,358
Shih Tzu 2,215
Cat (unknown) 1,903
Maltese 1,413
Shepherd Dog - German 1,371
Associated Drugs
Spinosad 12,856
Fluralaner 13.64% 12-Week Chew 7,207
Milbemycin Oxime + Spinosad 7,020
Nitenpyram 6,334
Fluralaner Chew Tablets 4,018
Afoxolaner 4,016
Selamectin 3,249
Fluralaner Spot-On Solution 2,965
Imidacloprid + Moxidectin 2,253
Pyrantel Pamoate;Sarolaner 1,546
Imidacloprid 1,081
Sarolaner 1,032
Selamectin;Sarolaner 644
Lotilaner 540
Fluralaner/Moxidectin Spot-On 525
Fipronil 455
Ivermectin 426
Imidacloprid, Flumethrin 391
Flumethrin-Imidacloprid 341
Milbemycin Oxime, Lufenuron 300
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.