Reaction profile

The FDA adverse-event record for congested mucous membrane

228 FDA adverse-event reports reference congested mucous membrane (VeDDRA 1007). See the species, breeds, and drugs most associated with it below.

228
reports citing this reaction
29.4%
death-coded share
Dog
most-affected species
Milbemycin Oxime + Spinosad
most-associated drug
Verify with FDA CVM →
228
Total Reports
67
Deaths
29.4%
Death Rate

Species Most Affected

Dog 178
Cat 24
Horse 22
Cattle 2
Human 1
Donkey 1

Breeds Most Affected

Domestic Shorthair 19
Retriever - Labrador 15
Chihuahua 13
Retriever - Golden 12
Boxer (German Boxer) 11
Crossbred Canine/dog 9
Quarter Horse 9
Terrier - Bull - American Pit 9
Terrier - Yorkshire 7
Dachshund (unspecified) 6

Associated Drugs

Milbemycin Oxime + Spinosad 31
Moxidectin 26
Maropitant Citrate 21
Deracoxib 12
Carprofen 10
Dexmedetomidine Hydrochloride 8
Isoflurane 7
Ceftiofur Crystalline Free Acid 7
Tramadol 7
Gabapentin 7
Pyrantel Pamoate;Sarolaner 7
Rabies Vaccine 6
Famotidine 6
Fluralaner Chew Tablets 6
Cefovecin 6
Rabies Virus, 6
Dexamethasone 5
Diphenhydramine 5
Nitenpyram 5
Spinosad 5

Congested mucous membrane Reaction Insights

228 reports name Congested mucous membrane; 67 recorded a death outcome (29.4% of reported events, not a population-level mortality rate). VeDDRA code: 1007.

By species: Dog (178 reports), Cat (24 reports), Horse (22 reports). By breed: Domestic Shorthair (19), Retriever - Labrador (15), Chihuahua (13).

Most co-reported drugs: Milbemycin Oxime + Spinosad (31 reports), Moxidectin (26 reports), Maropitant Citrate (21 reports), Deracoxib (12 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.