Reaction profile

The FDA adverse-event record for lack of efficacy (endoparasite) - cyathostominae

13 FDA adverse-event reports reference lack of efficacy (endoparasite) - cyathostominae (VeDDRA 2796). See the species, breeds, and drugs most associated with it below.

13
reports citing this reaction
15.4%
death-coded share
Horse
most-affected species
Pyrantel Pamoate;Sarolaner
most-associated drug
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13
Total Reports
2
Deaths
15.4%
Death Rate

Species Most Affected

Horse 7
Dog 5
Cattle 1

Breeds Most Affected

Thoroughbred 2
Mixed (Horse) 2
Saddlebred - American 1
Horse (unknown) 1
Cattle (unknown) 1
Warmblood (unspecified) 1
Canaan Dog 1
Mastiff 1
Shih Tzu 1
Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog) 1

Associated Drugs

Pyrantel Pamoate;Sarolaner 4
Pyrantel Tartrate 3
Fenbendazol Oral Paste 2
Ivermectin Pour-On Cattle 1
Fenbendazole 1
Praziquantel; Moxidectin 1
Milbemycin Oxime 1
Ivermectin + Pyrantel As Pamoate Salt 1

Lack of efficacy (endoparasite) - Cyathostominae Reaction Insights

13 reports name Lack of efficacy (endoparasite) - Cyathostominae; 2 recorded a death outcome (15.4% of reported events, not a population-level mortality rate). VeDDRA code: 2796.

By species: Horse (7 reports), Dog (5 reports), Cattle (1 reports). By breed: Thoroughbred (2), Mixed (Horse) (2), Saddlebred - American (1).

Most co-reported drugs: Pyrantel Pamoate;Sarolaner (4 reports), Pyrantel Tartrate (3 reports), Fenbendazol Oral Paste (2 reports), Ivermectin Pour-On Cattle (1 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.