Reaction profile

The FDA adverse-event record for hypoaesthesia

59 FDA reports name hypoaesthesia, a lower-volume reaction in the CVM extract (VeDDRA 1957). Plate stamps and neighbourhood peers follow.

#1657 of 2,481
by report volume (all reactions)
59
reports citing this reaction
11.9%
death-coded share
Human
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Hypoaesthesia has 59 reports now versus 58 in that prior snapshot: 1 more (1.7%).

Report change
+1
Death-coded reports
+1
Death-coded share
+1.5 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Hypoaesthesia changes

FDA AER · VeDDRA plate

Code 1957 VOL-LOW

VOL-LOW · DEATH-ELEV · MID-PACK · PHOTO-FINISH · SPECIES-HUMAN · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 59 reports
  • DEATH-ELEV 11.9%
  • MID-PACK #1657/2481
  • PHOTO-FINISH Hyposensitivity to pa…
  • SPECIES-HUMAN Human · 42
  • DRUG-LEAD Ivermectin · 6
  • DESK-WIDE 13 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Hyposensitivity to pain (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Lower-volume neighbourhood around Hypoaesthesia

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Hypoaesthesia · this reaction59Hyposensitivity to pa… · near59Injection site fibros… · near59Loss of smell · near59Low free thyroxine (F… · near59Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Hypoaesthesia

What the FDA AER plate says about Hypoaesthesia

Signature read: 7 death-coded reports is a thin tail count for Hypoaesthesia in the CVM extract. Report volume is lower-third scale: 59 named reports in the openFDA extract. 7 of 59 reports were death-coded (11.9% of named reports, not a population mortality rate). Nearest volume peer: Hyposensitivity to pain (±0 reports). Lead species Human (42). Lead co-reported drug Ivermectin (6).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Ivermectin appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Human 42
Dog 12
Horse 2
Cat 2
Guinea Pig 1

Breeds Most Affected

Unknown 43
Retriever - Labrador 5
Poodle (unspecified) 1
Dog (unknown) 1
Horse (unknown) 1
Dachshund (unspecified) 1
Thoroughbred 1
Domestic (unspecified) 1
Shepherd Dog (unspecified) 1
Crossbred Canine/dog 1

Associated Drugs

Ivermectin 6
Imidacloprid, Moxidectin 5
Tilmicosin Phosphate 4
Dexmedetomidine Hydrochloride 4
Spinosad 3
Ivermectin, Praziquantel 3
Pentobarbital, Phenytoin 3
Bedinvetmab 3
Maropitant 2
Florfenicol 2
Selamectin 2
Enrofloxacin 1
Deracoxib 1
Tiletamine, Zolazepam 1
Ceftiofur Hydrochloride 1
Ceftiofur 1
Milbemycin, Lufenuron 1
Nitenpyram 1
Doramectin 1
Imidacloprid + Moxidectin 1

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Hypoaesthesia, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (59 here).

Similar death-coded share

Nearest other reactions by death-coded share (11.9% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Hypoaesthesia (#1657 of 2,481 by report volume); death-coded 11.9%. PlainBreed reaction plate · death-coded report count stamp 7 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →