Reaction profile

The FDA adverse-event record for cardiac neoplasm

80 FDA adverse-event reports reference cardiac neoplasm (VeDDRA 2309). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1497 of 2,481
by report volume (all reactions)
80
reports citing this reaction
67.5%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Cardiac neoplasm has 80 reports now versus 80 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Cardiac neoplasm changes

FDA AER · VeDDRA plate

Code 2309 VOL-LOW

VOL-LOW · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 80 reports
  • DEATH-HOT 67.5%
  • MID-PACK #1497/2481
  • PHOTO-FINISH Dilated renal pelvis
  • SPECIES-DOG Dog · 77
  • DRUG-LEAD Milbemycin Oxime… · 18
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Dilated renal pelvis (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Report-volume neighbourhood around Cardiac neoplasm

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Cardiac neoplasm · this reac…80Dilated renal pelvis · near80Erythema multiforme · near80Hernia NOS · near80Hip dysplasia · near80Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Cardiac neoplasm

Cardiac neoplasm: high death-coded share in the FDA AER plate

Signature read: Cardiac neoplasm's 67.5% death-coded share is among the highest in the openFDA reaction corpus. Report volume sits in the middle third of the reaction corpus. Death-coded share is upper-third: 54 of 80 reports (67.5% of named reports). Nearest volume peer: Dilated renal pelvis (±0 reports). Lead species Dog (77). Lead co-reported drug Milbemycin Oxime + Spinosad (18).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 77
Cat 3

Breeds Most Affected

Retriever - Labrador 8
Crossbred Canine/dog 7
Retriever - Golden 5
Bulldog 5
Dog (unknown) 5
Boxer (German Boxer) 4
Shepherd Dog - Australian 3
Pug 3
Terrier - Boston 3
Shih Tzu 2

Associated Drugs

Milbemycin Oxime + Spinosad 18
Oclacitinib Maleate 15
Fluralaner Chew Tablets 6
Spinosad 5
Maropitant Citrate 5
Imidacloprid + Moxidectin 4
Pimobendan 4
Ivermectin + Pyrantel As Pamoate Salt 4
Carprofen 3
Cyclosporine 3
Trilostane 3
Deracoxib 3
Diphenhydramine Hcl 3
Polysulfated Glycosaminoglycan 2
Prednisolone; Trimeprazine Tartrate 2
Thyroxine 2
Moxidectin 2
Afoxolaner 2
Metronidazole 2
Cefovecin 2

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Cardiac neoplasm, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (80 here).

Similar death-coded share

Nearest other reactions by death-coded share (67.5% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Cardiac neoplasm (#1497 of 2,481 by report volume); death-coded 67.5%. PlainBreed reaction plate · death-coded share stamp 67.5% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →