Reaction profile

The FDA adverse-event record for mixed product other

63 FDA adverse-event reports reference mixed product other (VeDDRA 99958). See the species, breeds, and drugs most associated with it below.

63
reports citing this reaction
1.6%
death-coded share
Unknown
most-affected species
Afoxolaner
most-associated drug
Verify with FDA CVM →
63
Total Reports
1
Deaths
1.6%
Death Rate

Species Most Affected

Unknown 59
Dog 2
Cat 2

Breeds Most Affected

Unknown 59
Domestic Shorthair 2
Shepherd Dog (unspecified) 1
Dog (unknown) 1

Associated Drugs

Afoxolaner 15
Nitenpyram 5
Selamectin 4
Fluralaner 13.64% 12-Week Chew 4
Meloxicam 3
Levothyroxine Sodium 3
Fluralaner Spot-On Solution 3
Amoxicillin Anhydrous + Clavulanic Acid 2
Amoxicillin, Clavulanate 2
Insulin Injectable Vial 2
Ivermectin 272Mcg, Pyrantel Pamoate 228Mg, Praziquantel 228Mg 1
Hygromycin B 1
Pimobendan 1
Tylosin Tartrate 1
Oxytetracycline Hydrochloride 1
Monensin Sodium 1
Hyaluronate Sodium 1
Genta/Momet/Clotrim Ear Oint 1
Oclacitinib 1
Phenylpropanolamine Hydrochloride 1

Mixed Product Other Reaction Insights

63 reports name Mixed Product Other; 1 recorded a death outcome (1.6% of reported events, not a population-level mortality rate). VeDDRA code: 99958.

By species: Unknown (59 reports), Dog (2 reports), Cat (2 reports). By breed: Unknown (59), Domestic Shorthair (2), Shepherd Dog (unspecified) (1).

Most co-reported drugs: Afoxolaner (15 reports), Nitenpyram (5 reports), Selamectin (4 reports), Fluralaner 13.64% 12-Week Chew (4 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.