Mixed Product Other

Verify with FDA CVM →

VeDDRA Code: 99958

63 adverse event reports referencing this reaction

63
Total Reports
1
Deaths
160.0%
Death Rate

Species Most Affected

Unknown 59
Dog 2
Cat 2

Breeds Most Affected

Unknown 59
Domestic Shorthair 2
Shepherd Dog (unspecified) 1
Dog (unknown) 1

Associated Drugs

Afoxolaner 15
Nitenpyram 5
Selamectin 4
Fluralaner 13.64% 12-Week Chew 4
Meloxicam 3
Levothyroxine Sodium 3
Fluralaner Spot-On Solution 3
Amoxicillin Anhydrous + Clavulanic Acid 2
Amoxicillin, Clavulanate 2
Insulin Injectable Vial 2
Ivermectin 272Mcg, Pyrantel Pamoate 228Mg, Praziquantel 228Mg 1
Hygromycin B 1
Pimobendan 1
Tylosin Tartrate 1
Oxytetracycline Hydrochloride 1
Monensin Sodium 1
Hyaluronate Sodium 1
Genta/Momet/Clotrim Ear Oint 1
Oclacitinib 1
Phenylpropanolamine Hydrochloride 1

Data Summary

Metric Value
Total reports referencing reaction 63
Reports with fatal outcome 1
Case-fatality rate (reported events) 160.0%
Species observed 3
Breeds observed 4
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 99958.

Mixed Product Other Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 63 adverse event reports that reference Mixed Product Other as a reaction term, including 1 reports with a death outcome — a 160.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 99958, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Mixed Product Other appears most frequently in reports for Unknown (59 reports), Dog (2 reports), Cat (2 reports) — with Unknown dominating at 59 entries. Within those species, the breeds most often named alongside this reaction are Unknown (59), Domestic Shorthair (2), Shepherd Dog (unspecified) (1). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Mixed Product Other are Afoxolaner (15 reports), Nitenpyram (5 reports), Selamectin (4 reports), Fluralaner 13.64% 12-Week Chew (4 reports), with Afoxolaner appearing alongside this reaction in 15 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial